ID G1WJ35_9ACTN Unreviewed; 505 AA.
AC G1WJ35;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Threonine synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF9452_01348 {ECO:0000313|EMBL:EGX70359.1};
OS Collinsella tanakaei YIT 12063.
OC Bacteria; Actinomycetota; Coriobacteriia; Coriobacteriales;
OC Coriobacteriaceae; Collinsella.
OX NCBI_TaxID=742742 {ECO:0000313|EMBL:EGX70359.1, ECO:0000313|Proteomes:UP000004830};
RN [1] {ECO:0000313|EMBL:EGX70359.1, ECO:0000313|Proteomes:UP000004830}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIT 12063 {ECO:0000313|EMBL:EGX70359.1,
RC ECO:0000313|Proteomes:UP000004830};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Morotomi M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Collinsella tanakaei YIT 12063.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR604450-51};
CC -!- SIMILARITY: Belongs to the threonine synthase family.
CC {ECO:0000256|ARBA:ARBA00005517}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX70359.1}.
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DR EMBL; ADLS01000018; EGX70359.1; -; Genomic_DNA.
DR RefSeq; WP_009141383.1; NZ_JH126470.1.
DR AlphaFoldDB; G1WJ35; -.
DR STRING; 742742.HMPREF9452_01348; -.
DR GeneID; 62759061; -.
DR PATRIC; fig|742742.3.peg.1314; -.
DR eggNOG; COG0498; Bacteria.
DR HOGENOM; CLU_015170_3_1_11; -.
DR OrthoDB; 9778118at2; -.
DR Proteomes; UP000004830; Unassembled WGS sequence.
DR GO; GO:1901605; P:alpha-amino acid metabolic process; IEA:UniProt.
DR CDD; cd01560; Thr-synth_2; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.90.1380.10; Threonine synthase, N-terminal domain; 1.
DR InterPro; IPR029144; Thr_synth_N.
DR InterPro; IPR037158; Thr_synth_N_sf.
DR InterPro; IPR004450; Thr_synthase-like.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR00260; thrC; 1.
DR PANTHER; PTHR43515; THREONINE SYNTHASE-LIKE 1; 1.
DR PANTHER; PTHR43515:SF1; THREONINE SYNTHASE-LIKE 1; 1.
DR Pfam; PF00291; PALP; 1.
DR Pfam; PF14821; Thr_synth_N; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR604450-51};
KW Reference proteome {ECO:0000313|Proteomes:UP000004830}.
FT DOMAIN 4..79
FT /note="Threonine synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14821"
FT DOMAIN 88..432
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT MOD_RES 122
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR604450-51"
SQ SEQUENCE 505 AA; 53714 MW; EC540BE9AAEBF22A CRC64;
MATYHSTRSR TAQLSAKEAI RRGIAPDGGL YVSDELGQSK IDLEGLANKD YFELAREVLG
TLLPDYSADE IAACVDEAYG SSFASDEVTP VVDLKGVAGE ADQGNAPAYV MELWHGPTSA
FKDVALQMLP RLMARTSANA EGAADKIMIV TATSGDTGKA ALAGFADAPG CGITVFYPEG
KVSRVQELQM STQEGANVSV CAVRGNFDDA QSAVKRIFAD RELADRLAAA GVQLSSANSI
NVGRLVPQVV YYFAAYAQLL RAGKIQPGDA VEFCVPTGNF GDILAGYYAQ RLDLPVAKLI
VASDKNNVLF DFLTTGTYDR QRPFYTTTSP SMDILISSNL ERMLYYLADG DCELVAGLMT
QLAQGSYNVP AELLAKIQAV FGCGWADEDQ VAAAIKDCWD RNGYLIDPHT ACGYHVLGQV
PAASDAKARV VLSTASPYKF PRAVAGSLGL FCPPDDFACM KVLEKATGTV APAQLSELQQ
KPVLHDAVVD IDGMGGFVEQ AAAKL
//
