ID G1X2W5_ARTOA Unreviewed; 1244 AA.
AC G1X2W5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Antiviral helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AOL_s00043g38 {ECO:0000313|EMBL:EGX52544.1};
OS Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)
OS (Nematode-trapping fungus) (Didymozoophaga oligospora).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Orbilia; Orbilia oligospora.
OX NCBI_TaxID=756982 {ECO:0000313|EMBL:EGX52544.1, ECO:0000313|Proteomes:UP000008784};
RN [1] {ECO:0000313|EMBL:EGX52544.1, ECO:0000313|Proteomes:UP000008784}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24927 / CBS 115.81 / DSM 1491
RC {ECO:0000313|Proteomes:UP000008784};
RX PubMed=21909256; DOI=10.1371/journal.ppat.1002179;
RA Yang J., Wang L., Ji X., Feng Y., Li X., Zou C., Xu J., Ren Y., Mi Q.,
RA Wu J., Liu S., Liu Y., Huang X., Wang H., Niu X., Li J., Liang L., Luo Y.,
RA Ji K., Zhou W., Yu Z., Li G., Liu Y., Li L., Qiao M., Feng L., Zhang K.-Q.;
RT "Genomic and proteomic analyses of the fungus Arthrobotrys oligospora
RT provide insights into nematode-trap formation.";
RL PLoS Pathog. 7:E1002179-E1002179(2011).
CC -!- SIMILARITY: Belongs to the helicase family. SKI2 subfamily.
CC {ECO:0000256|ARBA:ARBA00010140}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX52544.1}.
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DR EMBL; ADOT01000056; EGX52544.1; -; Genomic_DNA.
DR RefSeq; XP_011118827.1; XM_011120525.1.
DR AlphaFoldDB; G1X2W5; -.
DR STRING; 756982.G1X2W5; -.
DR GeneID; 22890085; -.
DR eggNOG; KOG0947; Eukaryota.
DR HOGENOM; CLU_002902_1_4_1; -.
DR InParanoid; G1X2W5; -.
DR OMA; CGSDITR; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000008784; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 1.20.1500.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008784};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 297..453
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 571..771
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 494..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1244 AA; 139825 MW; 8655C75923EC0A15 CRC64;
MATIYNFDIE RAGEINIDAP LGSPKPRPPI KRRREERLDD LEHNFLTPLD QFPVEWLNNL
QERWEDPPDY YSLFALSSTM TRTVIRFTRE GLEGRVTGYK EVSVPAQSIN AKNSTSLLRK
PGTRADFVRG KAGFFPFAPG GLEVGSSNEV SEDLAAVEFA QDSLYGRDGM LQIAPGLLRG
LGVEGDGEPD EDEDDDGFQF GDVKPIRQLK DVLGSNERRV QSTVAISELE GIDDLLPVEF
PLLAPRGQLA PSSAVSRGKE WAHMVDINQD LTNFKELVPN MAREWTFELD NFQKEAVYHL
ENGDSVFVAA HTSAGKTVVA EYAIALAAKH MTKAIYTSPI KALSNQKFRD FRNIFDDVGI
LTGDVQINPE ASCLIMTTEI LRSMLYRGAD LIRDVEFVIF DEVHYVNDQE RGVVWEEVII
MLPDHVNLIL LSATVPNTQE FASWVGRTKK KDIYVISTPK RPVPLEHYLW AGKKMHKIVD
QNKKFLETGL RDANEAMSGK KDERPNQSVP TRGNISQRGG QRGGPNHRGS QSARGGRGGN
VMRGASGAAS FNRGGRGGRT TANQDKNLWV HLVQHLKKED LLPGCIFVFS KKRCEENADA
LSNLDYCTAN EKSAIHMIVE KSIARLRIED RQLPQIRRLR DLLSRGIAVH HGGLLPIVKE
MVEILFAKSL VKVLFATETF AMGLNLPTRT VVFSGIRKHD GRSFRDLLSG EYIQMAGRAG
RRGLDSSGTV IIVGNGDEAP PAGTLKTMIL GQPTKLQSQF RLTYNMILNL LRVEALKIEE
MIKRSFSENA TQTLLPEHQK MVTANEEGLK KLIREDCIYC NEDLDTLHEA GITYKKLTQE
LHTLALKNPQ GKRMYCSGRV IILQDKDSTR TIGVLIRPSQ TTGADPVIQI LKLTGGNDQK
IPGDAVPFNP LFAPVIRQVA GDKVKIKETA VPLSQIEYIS KTVVDARITE ARTGKAAVVK
QLLQELKELG QGLDDSAWTE NDWTKIRDMR FQEVMKGRKA ELQKIKKCKS LSCPKFAKHF
RARNEEYKLQ EKIKNLKQLI SDQNLQLLPD YEQRVRVLKQ LDFIDESSRV QLKGRVACEI
NSANELVLTE LILENTLADF EPEEMVALLS AFVFQEKTDT VPVVPPKLER GKEKILEIAK
RVNEIQSEHQ VLINAETDDF EGRPRFGLME VVYEWAKGMS FERITDLTDV LEGTIVRVIT
RLDETCREVR NAARIIGDPA LYQKAEKCQE IIRRDIISCG SLYF
//
