ID G2DWZ7_9GAMM Unreviewed; 270 AA.
AC G2DWZ7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=formylmethanofuran dehydrogenase {ECO:0000256|ARBA:ARBA00012692};
DE EC=1.2.7.12 {ECO:0000256|ARBA:ARBA00012692};
GN ORFNames=ThidrDRAFT_0558 {ECO:0000313|EMBL:EGV33351.1};
OS Thiorhodococcus drewsii AZ1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiorhodococcus.
OX NCBI_TaxID=765913 {ECO:0000313|EMBL:EGV33351.1, ECO:0000313|Proteomes:UP000004200};
RN [1] {ECO:0000313|EMBL:EGV33351.1, ECO:0000313|Proteomes:UP000004200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AZ1 {ECO:0000313|EMBL:EGV33351.1,
RC ECO:0000313|Proteomes:UP000004200};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Imhoff J., Thiel V.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RT "The draft genome of Thiorhodococcus drewsii AZ1.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + N-formylmethanofuran + 2 oxidized [2Fe-2S]-[ferredoxin]
CC = CO2 + H(+) + methanofuran + 2 reduced [2Fe-2S]-[ferredoxin];
CC Xref=Rhea:RHEA:19841, Rhea:RHEA-COMP:10000, Rhea:RHEA-COMP:10001,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526,
CC ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57727,
CC ChEBI:CHEBI:58151; EC=1.2.7.12;
CC Evidence={ECO:0000256|ARBA:ARBA00000989};
CC -!- PATHWAY: One-carbon metabolism; methanogenesis from CO(2); 5,10-
CC methenyl-5,6,7,8-tetrahydromethanopterin from CO(2): step 1/3.
CC {ECO:0000256|ARBA:ARBA00004830}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGV33351.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AFWT01000003; EGV33351.1; -; Genomic_DNA.
DR RefSeq; WP_007039274.1; NZ_AFWT01000003.1.
DR AlphaFoldDB; G2DWZ7; -.
DR STRING; 765913.ThidrDRAFT_0558; -.
DR eggNOG; COG2218; Bacteria.
DR OrthoDB; 8562860at2; -.
DR Proteomes; UP000004200; Unassembled WGS sequence.
DR GO; GO:0018493; F:formylmethanofuran dehydrogenase activity; IEA:InterPro.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR Gene3D; 2.160.20.60; Glutamate synthase, alpha subunit, C-terminal domain; 2.
DR InterPro; IPR017550; Formylmethanofuran_DH_suC.
DR InterPro; IPR002489; Glu_synth_asu_C.
DR InterPro; IPR036485; Glu_synth_asu_C_sf.
DR NCBIfam; TIGR03122; one_C_dehyd_C; 1.
DR PANTHER; PTHR39673; TUNGSTEN FORMYLMETHANOFURAN DEHYDROGENASE, SUBUNIT C (FWDC); 1.
DR PANTHER; PTHR39673:SF7; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT C; 1.
DR Pfam; PF01493; GXGXG; 1.
DR SUPFAM; SSF69336; Alpha subunit of glutamate synthase, C-terminal domain; 1.
PE 4: Predicted;
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994};
KW Oxidoreductase {ECO:0000313|EMBL:EGV33351.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 82..207
FT /note="Glutamate synthase alpha subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01493"
SQ SEQUENCE 270 AA; 28400 MW; 4DE677E1CD266DB1 CRC64;
MSALTLRLRE CPRQRIDLSG FTSDALAGKS LADIQALPLW VGNRQMPAGD LFIIHGHDSD
HIRIESESDR LDGIGSGMTR GSIRIQGHAG AYLGRGMRGG EIQVEGDASL FAGTGMTGGL
LRIGGNAGDF LGAAIPGERR GLRGGRIEVR GNAGERVGDR QRRGMILIAG NAGDYCGSRM
GAGTILVLGQ TGANVGFAMR RGTILLTSAP ELPPTFNDNG PQDLSVLTLL AKSLPSPFDQ
IGERGTRVQR WLGDLGHGGQ GEVLAWPPLT
//
