ID G2E244_9GAMM Unreviewed; 173 AA.
AC G2E244;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Lipopolysaccharide export system protein LptA {ECO:0000256|HAMAP-Rule:MF_01914};
DE Flags: Precursor;
GN Name=lptA {ECO:0000256|HAMAP-Rule:MF_01914};
GN ORFNames=ThidrDRAFT_2357 {ECO:0000313|EMBL:EGV30993.1};
OS Thiorhodococcus drewsii AZ1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Thiorhodococcus.
OX NCBI_TaxID=765913 {ECO:0000313|EMBL:EGV30993.1, ECO:0000313|Proteomes:UP000004200};
RN [1] {ECO:0000313|EMBL:EGV30993.1, ECO:0000313|Proteomes:UP000004200}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AZ1 {ECO:0000313|EMBL:EGV30993.1,
RC ECO:0000313|Proteomes:UP000004200};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Vogl K., Liu Z., Imhoff J., Thiel V.,
RA Frigaard N.-U., Bryant D.A., Woyke T.J.;
RT "The draft genome of Thiorhodococcus drewsii AZ1.";
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in the assembly of lipopolysaccharide (LPS).
CC Required for the translocation of LPS from the inner membrane to the
CC outer membrane. May form a bridge between the inner membrane and the
CC outer membrane, via interactions with LptC and LptD, thereby
CC facilitating LPS transfer across the periplasm. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|HAMAP-Rule:MF_01914}.
CC -!- SIMILARITY: Belongs to the LptA family. {ECO:0000256|HAMAP-
CC Rule:MF_01914}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGV30993.1}.
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DR EMBL; AFWT01000015; EGV30993.1; -; Genomic_DNA.
DR RefSeq; WP_007041070.1; NZ_AFWT01000015.1.
DR AlphaFoldDB; G2E244; -.
DR STRING; 765913.ThidrDRAFT_2357; -.
DR eggNOG; COG1934; Bacteria.
DR OrthoDB; 9795964at2; -.
DR Proteomes; UP000004200; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0001530; F:lipopolysaccharide binding; IEA:InterPro.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01914; LPS_assembly_LptA; 1.
DR InterPro; IPR014340; LptA.
DR InterPro; IPR005653; OstA-like_N.
DR NCBIfam; TIGR03002; outer_YhbN_LptA; 1.
DR PANTHER; PTHR36504; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR PANTHER; PTHR36504:SF1; LIPOPOLYSACCHARIDE EXPORT SYSTEM PROTEIN LPTA; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Periplasm {ECO:0000256|ARBA:ARBA00022764, ECO:0000256|HAMAP-Rule:MF_01914};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|HAMAP-Rule:MF_01914};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_01914}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01914"
FT CHAIN 34..173
FT /note="Lipopolysaccharide export system protein LptA"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01914"
FT /id="PRO_5009012664"
FT DOMAIN 44..152
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
SQ SEQUENCE 173 AA; 19374 MW; AF3E798BA8712E82 CRC64;
MITFKADRTR TPRPIARLLL AALTVLSAGQ SWALKDDAKQ PILIEADDVE VRESDSTSVY
VGNVQVDQGS MQLLADHVTV YHREDRQPKF IIALGKPARY KQRLDGDQGE VHAFAKRIEY
NADKDELVLI GDGVLIQGED RLTSERIIYD RARAQFRAGG SGRVKITITP EEQ
//
