ID G2G1I2_9FIRM Unreviewed; 528 AA.
AC G2G1I2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Squalene cyclase C-terminal domain-containing protein {ECO:0000259|Pfam:PF13243};
GN ORFNames=DOT_5867 {ECO:0000313|EMBL:EGW36240.1};
OS Desulfosporosinus sp. OT.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Desulfosporosinus.
OX NCBI_TaxID=913865 {ECO:0000313|EMBL:EGW36240.1, ECO:0000313|Proteomes:UP000004928};
RN [1] {ECO:0000313|EMBL:EGW36240.1, ECO:0000313|Proteomes:UP000004928}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT {ECO:0000313|EMBL:EGW36240.1,
RC ECO:0000313|Proteomes:UP000004928};
RX PubMed=21994931; DOI=10.1128/JB.06018-11;
RA Abicht H.K., Mancini S., Karnachuk O.V., Solioz M.;
RT "Genome Sequence of Desulfosporosinus sp. OT, an Acidophilic Sulfate-
RT Reducing Bacterium from Copper Mining Waste in Norilsk, Northern Siberia.";
RL J. Bacteriol. 193:6104-6105(2011).
CC -!- PATHWAY: Secondary metabolite biosynthesis; hopanoid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004999}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGW36240.1}.
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DR EMBL; AGAF01000264; EGW36240.1; -; Genomic_DNA.
DR RefSeq; WP_009624518.1; NZ_AGAF01000264.1.
DR AlphaFoldDB; G2G1I2; -.
DR PATRIC; fig|913865.3.peg.5394; -.
DR eggNOG; COG1657; Bacteria.
DR OrthoDB; 9758578at2; -.
DR UniPathway; UPA00337; -.
DR Proteomes; UP000004928; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR001330; PFTB_repeat.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR PANTHER; PTHR11764:SF20; LANOSTEROL SYNTHASE; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR Pfam; PF00432; Prenyltrans; 3.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 289..450
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 528 AA; 58520 MW; 966AEF3F01067C09 CRC64;
MDLKNEVQEG LNNARHFVVD GVEQILSGNL DETHGVSPSP GATALAALAL LAVGRGFETA
QQRGIQWLRQ NRQGGWGKFP GDKPDEEITQ IVETVLQGSQ GGWMARIIIL SQARQFSQMI
LSLGQRVVPG LEGPTPEEIL LPTILEDRIL AKLPLYGRPV VVAASLLASN SQEGSQKGIQ
YLLKTQMSDG SWAEDIIATS LSILALMNKG GYAEQTQRAG RWLVQKQYPG GGWPAFDQLK
IWAIGWAASV FGETAQRPAD IPWIGQAVDW LKRGQNVDGS YGSTPPYTHP DLDDTAVALI
GLHQVLGEQN QLGVSLLKRL QNTDGSWGTF PSFQGTPPQV SSELPVYIPS VDVSIHVLEA
LWWRTRTQDE KIWRGINWIL AQQDDQGAFP ASWFEGPVYS TAQALELLSK WKFSWERWNT
ARHILGARKK AQEFLIKAQS SDGGWGSVVE TSLSLSGLWR YTRIVPRGVL EKGIRNLLAA
QNSNGSFEPS YRGVYAKGWN YEEPLTTTLT AIRALQRYQR LYKASFFR
//
