ID G2GFB3_9ACTN Unreviewed; 561 AA.
AC G2GFB3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=SZN_20986 {ECO:0000313|EMBL:EGX57815.1};
OS Streptomyces zinciresistens K42.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=700597 {ECO:0000313|EMBL:EGX57815.1, ECO:0000313|Proteomes:UP000004217};
RN [1] {ECO:0000313|EMBL:EGX57815.1, ECO:0000313|Proteomes:UP000004217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K42 {ECO:0000313|EMBL:EGX57815.1,
RC ECO:0000313|Proteomes:UP000004217};
RA Lin Y., Hao X., Johnstone L., Miller S.J., Wei G., Rensing C.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX57815.1}.
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DR EMBL; AGBF01000077; EGX57815.1; -; Genomic_DNA.
DR AlphaFoldDB; G2GFB3; -.
DR PATRIC; fig|700597.3.peg.4122; -.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000004217; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EGX57815.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004217}.
FT DOMAIN 24..153
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 157..504
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 534..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 335
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 561 AA; 61834 MW; E3D1980C791AC7AA CRC64;
MTSLTEPTEP TEPTEPTGPT EPAELIPAPR AAAAPAAGGV TLDQDTTLWA APGTGTTERW
LRAALGAAFA LPLRPGPADR PGGVRLRLDD TMEPEAYRLT VAAPDGVEIR GGGPAGVFWG
AQTLRQLLGP DAFRRAPVRP GAPLRIAPVT VEDAPRFGWR GLMLDVARHF MPKDGVLRYL
DLMAAHKLNV LHFHLTDDQG WRIEIARYPR LTETGSWRAR TKFGHRASPL WDEKPHGGHY
TQDDIREIVS YAAERHITVV PEIDVPGHSQ AAIAAYPELG NTDVVDTAAL AVWDDWGISP
NVLAPTDRTL RFYEGVFEEV LELFPAPFVH VGGDECPKDQ WRRSPAAQER IRELGLGDED
GLQAWFIRHF DTWLTARGRR LIGWDEILEG GLAPGAAVSS WRGYAGGIAA ARAGHDVVMC
PEQQVYLDHR QDAGADEPVP IGYVRTLEDV YRFEPVPAEL TSEEARHVLG TQANVWTEVM
EDHARVDYQT FPRLAAFAEV AWSALPAPAE RDFAAFERRM GAHYRRLDAL GVAYRPPSGP
RPWQRRPGVL GRPIDGPPPN R
//
