ID G2GN31_9ACTN Unreviewed; 925 AA.
AC G2GN31;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Integral membrane sensor protein {ECO:0000313|EMBL:EGX55086.1};
GN ORFNames=SZN_34682 {ECO:0000313|EMBL:EGX55086.1};
OS Streptomyces zinciresistens K42.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=700597 {ECO:0000313|EMBL:EGX55086.1, ECO:0000313|Proteomes:UP000004217};
RN [1] {ECO:0000313|EMBL:EGX55086.1, ECO:0000313|Proteomes:UP000004217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K42 {ECO:0000313|EMBL:EGX55086.1,
RC ECO:0000313|Proteomes:UP000004217};
RA Lin Y., Hao X., Johnstone L., Miller S.J., Wei G., Rensing C.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX55086.1}.
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DR EMBL; AGBF01000270; EGX55086.1; -; Genomic_DNA.
DR RefSeq; WP_007504200.1; NZ_AGBF01000270.1.
DR AlphaFoldDB; G2GN31; -.
DR PATRIC; fig|700597.3.peg.6763; -.
DR Proteomes; UP000004217; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd16936; HATPase_RsbW-like; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13581; HATPase_c_2; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR Pfam; PF07228; SpoIIE; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004217};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 266..331
FT /note="PAS"
FT /evidence="ECO:0000259|SMART:SM00091"
FT DOMAIN 396..560
FT /note="GAF"
FT /evidence="ECO:0000259|SMART:SM00065"
FT DOMAIN 578..798
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|SMART:SM00331"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 925 AA; 99221 MW; 82B6C37EDA4B5D9D CRC64;
MVRLWGRSAA RSPRRPSGPR TRPAPDRGRP LPARGPLDET PAEGRRKGLL ASVRSRAGGR
SLAGQVFLLQ VVIVLLLVVA AVVALVLQVR YDSTQEARNR SVAVAEAFAN APGTREALDS
PDPTAVLQPK AEAARRATGV DYVVVLNTHG IRYTHPRPDR IGKRFVGTFR PALAGKVVTE
QVTGTIGPLV NAVVPIKDPG GKVVGLVSAG ITTATVGGTA DRQLPLVLIT AAVALALSTF
GTALVSRRLL RQTHGLGPDE MTRMYEHHDA VLHAVREGVI IVGGEGRLLL ANDEAHRLLG
LPQDAQGDRV LDLSLPPDTA ELLESGRTAT DEVHLVKDRL LAVNQRPTRL RGRPSGSVTT
LRDSTELRAL SGRAEEARER LDMLYDAGVG IGTSLDVTRT AEELAELAVP RFADYTTVDL
YDGVLGGGQP EAVTRLRRTA LSGVRADAPL YPVGERFRFV DTSPQARALK EGHALVEPRL
DQAPGWRAQD LERSGQIVDF GIHSLIAVPL RAGALVLGVV CFWRSRGTEP FDAEELALAE
ELVARAAVSI DNARRYTREH GMAVTLQRSL LPRRLPEQSA LDIAYRYLPA QAGVGGDWFD
VLPLSGARVA LVVGDVVGHG LHAAATMGRL RTAVHNFSAL DLPPDELLGL LDELVARIDQ
DETADGDSAP VTGATCLYAV YDPVSRRCTV ARAGHPPPAV VRPDGSVDFP DVPAGPPLGL
GGLPFETAEL ELAEDSRLVL YTDGLVEDRA HDIEEGLELL RAALTGAGRS PEETCRAVLE
ARLPARPSDD VALLVARTRA LGPDLVAEWE VPSDPQAVAR VRAAVTRTLE GWGLAELSFG
TELILSELVT NAIRYGGEPI RVRMLRDRSL ICEVFDSSST SPHLRYAAMT DEGGRGLFLV
AQLAERWGTR YLPAGKVIWA AQPLP
//
