ID G2GP48_9ACTN Unreviewed; 748 AA.
AC G2GP48;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Integral membrane export protein {ECO:0000313|EMBL:EGX54719.1};
GN ORFNames=SZN_36519 {ECO:0000313|EMBL:EGX54719.1};
OS Streptomyces zinciresistens K42.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=700597 {ECO:0000313|EMBL:EGX54719.1, ECO:0000313|Proteomes:UP000004217};
RN [1] {ECO:0000313|EMBL:EGX54719.1, ECO:0000313|Proteomes:UP000004217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K42 {ECO:0000313|EMBL:EGX54719.1,
RC ECO:0000313|Proteomes:UP000004217};
RA Lin Y., Hao X., Johnstone L., Miller S.J., Wei G., Rensing C.;
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGX54719.1}.
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DR EMBL; AGBF01000341; EGX54719.1; -; Genomic_DNA.
DR RefSeq; WP_007505289.1; NZ_AGBF01000341.1.
DR AlphaFoldDB; G2GP48; -.
DR PATRIC; fig|700597.3.peg.7092; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000004217; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000004217};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..748
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038914438"
FT TRANSMEM 177..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 593..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 197..326
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 748 AA; 77550 MW; 795052E85E8F596B CRC64;
MAALARWCVR RRLVAVLLWL LAFGGVTAAA AVAGTAYSND YEVPGTESGR ATQLLADGFP
GLGGDGDTVV WRTGTGTVRA AAVEQTMTRT LDEMAGLPGV ASVGSPYTKQ GAAQISEDGR
TAYATVAFEG GAQNLSEGEA RALVDTARTA EGDGLQVALG GSGVALTQAP GGKTAEIVGV
AVAAVVLFLA FGSLAASLLP IATALVSVGT AYAGIALLGH VMTVADFAPM LGMLVGLGVG
IDYALFIVTR HRRGLKRGLP VAESITQAVA TTGRAVVFAG ATVCIALLGM LILRLSFLNG
VAIAASLTVI LTVAASVTLL PALLSFIGMR ALSRRERRRL AEHGPEPEVP TGFAARWSAF
VERHPKALGA VALAVIAVLA LPTLGLRLGT SDQGNDPQGS TTRQAYDLLA DGFGPGVNGP
LTLVTEVDGG DDKLALDGLD ATLRATEGVA AATPVTYNAG GDTAYLTVVP ESAPQSRQTS
ELVDRLREDV LPRAESGTSL DVQVGGMTAG YDDFADVIVG KLPLFVGVVI GLGCLLLLLA
FRSVGIPLKA AAMNVAAVAA AFGVVVAVFQ WGWGSELLGL GRAGPIEPFL PVIMVSVLFG
LSMDYQVFLV SRMYEEWLET GDNRRAVRVG LAETSRVINS AAVIMISVFL AFVLSGDRVI
AMFGIALAAA VALDAFVLRT LLVPALMHLL GGANWWLPRW LDRRMPRISI EPPESRAAHE
RLAAATDAEA ADVLAREERK PDVRDTAG
//
