ID G2GX26_9ENTR Unreviewed; 2262 AA.
AC G2GX26;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=RTX toxin {ECO:0000313|EMBL:EGY29701.1};
GN ORFNames=Rin_00023541 {ECO:0000313|EMBL:EGY29701.1};
OS Candidatus Regiella insecticola 5.15.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Regiella.
OX NCBI_TaxID=1005043 {ECO:0000313|EMBL:EGY29701.1, ECO:0000313|Proteomes:UP000004116};
RN [1] {ECO:0000313|EMBL:EGY29701.1, ECO:0000313|Proteomes:UP000004116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R5.15 {ECO:0000313|Proteomes:UP000004116};
RX PubMed=21948522; DOI=10.1101/gr.125351.111;
RA Hansen A.K., Vorburger C., Moran N.A.;
RT "Genomic basis of endosymbiont-conferred protection against an insect
RT parasitoid.";
RL Genome Res. 22:106-114(2012).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGY29701.1}.
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DR EMBL; AGCA01000061; EGY29701.1; -; Genomic_DNA.
DR PATRIC; fig|1005043.3.peg.291; -.
DR OrthoDB; 1676884at2; -.
DR Proteomes; UP000004116; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00118; LysM; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.10.350.10; LysM domain; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 8.
DR InterPro; IPR041690; Cadherin_5.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR010566; Haemolys_ca-bd.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR Pfam; PF17892; Cadherin_5; 1.
DR Pfam; PF06594; HCBP_related; 1.
DR Pfam; PF00353; HemolysinCabind; 9.
DR Pfam; PF01476; LysM; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00313; CABNDNGRPT.
DR SMART; SM00257; LysM; 1.
DR SUPFAM; SSF51120; beta-Roll; 4.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF54106; LysM domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 5.
DR PROSITE; PS51782; LYSM; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000004116};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 237..282
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 1352..1493
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
SQ SEQUENCE 2262 AA; 242713 MW; DA52BB9850DF1723 CRC64;
MNDKQPEDDM SIYKSSIEFT FKMSSELAGE GTKLAAEAMR DSFELARKSG DLAAILATSA
GAMKLKLIHI GIVNGEDIYK LVAAFNSNDP AGVAKVTYVV AAGALAGSVT KLAFVPLKLT
TPLGKIASWV APAITGYAAG KWADNDWDNV RKSSESGKAV TYQIGKLFSL EVKAEGFNAP
SLISDETHFA LAKNISRLVS VGVGLGDKLT KGITDVNRYL REASVWSDLN FKPVPFHDYS
VKSGDTLTHI AKRNNISLRE LLKLNPEIKN PNFIKTGEKI KLPDVKNDFL LSVDNKAERA
NNKNFDPIEN TNRVSSGVVA SGGSWSLLFD PARLNIDNLL LNANPSGNDP LAKTVFNPNY
HIDNTINAAI GNILSDGYRP GNGNLAKSVF DPKYLLKDNI PTPKETMSHF CWINSLSLLS
KQTFPTDPLV LDLNDDGVRL TDYASSPILF DIDNDGGELE ETGWVSPEDG LLVHDLNKNG
KIDNIGEIFS EYYAGKSGQT GEAGEKLFGH GFAALATLDS NNNRQFETQD QAWKEVRIWQ
DKNHNGQTDE GELLTLDQLK ISAINLVAQI QSGELLDNNE VLARGTFTQN GAQKMVLAAN
FLANPRGHTF TAAEQGIKVV TGGDPRAGSV TAFVSRSDSG ETLVADKLGV VNITGGKGDD
TLTGNAKNNW LAGGLGSDTF FGGDGDDVLL IDAEDRPENI HGGAGRDIVY VLGDQGIYLD
VFKAEVEMAI GGRGDDFFIA NGNSTVYLQG GEGNDVLMGG TAADVLAGES GDDNLFAGAG
NDVLRGHKGN DRLYGGLDDD LLEGGSGSDT LYGGDGDDIL KGGAGDDFLD GGEGHDVVEF
SGDLADYTFT KIRDGFLVSD QIAGRDGTDT IKNVEKANFK NISGIDITQT SENPYPVNDF
LKKDKHSKVF GSSYSYTIGQ TQLLGNDIDF HGDTLKIAGL SDVVGGTAIL KNDGDIWFIP
HRQFRGIPSF KYTITDSKGN PGLTVVETGT ENRAEIRAQV FLIPSHLPDD PLLVEALHLA
QTSVLPVWKH YTGKGVKIGQ FEPSNEFSMG KELADFQHPE LRENTDKNWL ANHNPDEYVA
VSDHATMVAG VMVGAKNHEG GIGVAHEATW GGHWIHKDEF SSLAMMKHYD VVNHSWGPSG
SFDLKFLPTG LNSTPGAFIQ ALVKGRHGLG TVIVVGGGNK RTTGENTNYS NLSNTRHSIT
VGATSVEGDL SLLVKNSQPF SNPGASILVS APGNNISTSS TPKTNKNETV FGDEKIKTQG
TSFSAPIVSG IVALMLEANP DLGYRDIQDI LAVSARKVKD GKTHWAENGS RTWNGGGMHI
SHDYGYGMVD AQAAVRLAEN WTTQQTYLNE TFLREQLLSG ELNVALPDAT PQGSGLYTHK
LTVENSDIVI ENVEIRVALT HAQAGDLTLK LISPVGTESV LMHRPGKAPG SHDSARGDKL
FYNEDSLDYV FSSALLRGEQ ADGEWQLQVI DNIIGATGRF KNWSMNFYGK PGAANNQYIY
TDEYTASEDR NTLHAANDGS DIINVAAISG TVQIDLQTGR CSLNVQPLTI TQPNNIRKVV
TGDFNDILTG NELNNILVGG RGDDRLFGEG GHDVLIGSQG NDILTGGGGN DDFVIDRVAG
DKDIITDFTV GQDKLVLSGF KSLSTLNIEQ QGENTLLELA DGQRVQFNHI QATSLTKDCF
VVSEEKVSIQ KLNDATGYKM GTVGEMTLPN ISGLHVWADF SGDKIFGGNR NDTLYGGPSA
DILVGEASTN SETGGNDIIY GGAGTDIVRG GPGDDTLYGG DGLDYLGGDA GNDILYLEGD
DGGIPSLMEG AILDDITLNI GEALSGAAVT GGAGNDRFVL VNDPTLNNAQ GLLKNLIMDF
EVNNPKEKID LSQFNATRSF TDLSFNTITF NGEGYLRVWI GSQEEKGSAY FTLKGITKKQ
LSAKNFIFNT SHVNRQAEFI GTNGNDRLIG NAGGNLLDGK GGIDILEGRS GNDTYLIANT
QTHVIEVANG GHDRVKSSVT FTLPNHVEDI YLLGERAINA MGNTLNNRLI GNAADNQLDG
KGGIDIMIGG KGNDTYFVDH ELDRVIEHED EGQDKVHSLV SFTLPSHVEI LVLTGEASVN
GTGNHLNNTI EGNAGHNCLL GGKGDDILSG HVGNDVLEGG IGNDTYFFTP GDGQDVIYDI
AGSDKLVLDI DYKKLWFSYS GNDLIVAIIG TGDKITLADW KHESKAHHIE RFEQKGGSYL
DHSKIDHLIN TMASFAPPPA GQTSLSNEYK RVLEPVITAS WQ
//
