ID G2GXI0_9ENTR Unreviewed; 1180 AA.
AC G2GXI0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Glycosyltransferase {ECO:0000313|EMBL:EGY29542.1};
GN ORFNames=Rin_00004720 {ECO:0000313|EMBL:EGY29542.1};
OS Candidatus Regiella insecticola 5.15.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; aphid secondary symbionts; Regiella.
OX NCBI_TaxID=1005043 {ECO:0000313|EMBL:EGY29542.1, ECO:0000313|Proteomes:UP000004116};
RN [1] {ECO:0000313|EMBL:EGY29542.1, ECO:0000313|Proteomes:UP000004116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R5.15 {ECO:0000313|Proteomes:UP000004116};
RX PubMed=21948522; DOI=10.1101/gr.125351.111;
RA Hansen A.K., Vorburger C., Moran N.A.;
RT "Genomic basis of endosymbiont-conferred protection against an insect
RT parasitoid.";
RL Genome Res. 22:106-114(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGY29542.1}.
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DR EMBL; AGCA01000103; EGY29542.1; -; Genomic_DNA.
DR RefSeq; WP_006706174.1; NZ_AGCA01000103.1.
DR AlphaFoldDB; G2GXI0; -.
DR OrthoDB; 5489595at2; -.
DR Proteomes; UP000004116; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.140.180; -; 2.
DR Gene3D; 3.40.50.11550; -; 1.
DR Gene3D; 3.90.550.20; -; 1.
DR InterPro; IPR020972; Dermonecrotic/RTX_toxin_MLD.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR024770; TcdA/TcdB_cat.
DR InterPro; IPR048461; ToxA-like_C2.
DR Pfam; PF11647; MLD; 1.
DR Pfam; PF20899; PMT_C2; 1.
DR Pfam; PF12919; TcdA_TcdB; 1.
DR SUPFAM; SSF159501; EreA/ChaN-like; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF158842; PMT central region-like; 2.
PE 4: Predicted;
KW Host membrane {ECO:0000256|ARBA:ARBA00022870};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000004116};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Toxin {ECO:0000256|ARBA:ARBA00022656};
KW Transferase {ECO:0000313|EMBL:EGY29542.1};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 104..471
FT /note="GT44"
FT /evidence="ECO:0000259|Pfam:PF12919"
FT DOMAIN 819..1056
FT /note="Dermonecrotic toxin-like C2"
FT /evidence="ECO:0000259|Pfam:PF20899"
FT DOMAIN 1090..1145
FT /note="Dermonecrotic/RTX toxin membrane localization"
FT /evidence="ECO:0000259|Pfam:PF11647"
FT REGION 1157..1180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1180 AA; 135335 MW; 9ED261ABD66A4E19 CRC64;
MTERNSHESS GIENNNQRHD YNEIKKAQTH YQEQLNSIQN SLEEWELLKE INQKIHRYIE
KYPLVGSDEV EHLRSEEIKQ LLAQNQQRNR ELAIMPELRR EIPKKIHFVW LGKLGTIQQE
YIRAWNEINK GENYTITIWY DKDALLVHEL NKRIKAFAKK INQLNFTPDA YANAVIVIQN
QAYQKITEAL ERGLTFDQAS INFIRDYLKG DEQELRNIKK QNQASFDDFI LNERKAGRHY
TLKNVKSLFD IDPHNPNPVQ DREIQIQQKN YQLELALRQN MAAASDMLRL KVLEQQGGGY
FDADLLPAFK ADLWENLEIP AALSKSDLND TDFNLAKTQL VLEHLSEFFP HRKMLFDSNK
YQDYAKSFAA KGSAHKKLID DMRIFLRGKR NTLSDFFQPL QPIKLHPDGI LVAKNRDVFI
NNNAIFSYPN SGSIKLLQQQ IGNNYRFLRD HDLVFVDNTD VINDRINNYT DKITLALWND
PKASTRINGE IGNMLFRKDG VVPGSQATIF ISGPEMFERR IKRYSEQMFG QQRNPLSSSA
EASFFISGLF SDFNNFTEED MVSSWIQETE ASSQTLLIKR SDQLKEWSAL DIQNKPHQGN
ANQEKLYNDI RHHFDTLFLE NTDKKILKNI FSLQLKIQSY INNYPKFPSV AALKELQKKI
HNIVFPDADF KLNQQRSIII ISKIDPEQAA RIYMSIHDHN KYGKAEPNIN ALIFSDPYLQ
PFKGFTGEEN DIFQGKQGDF NAKFHIPLGN KFTVFKANLL AAQAQNVLNN VYLDEKKIAH
IGYSYNELTA LKGNEHVGII IYTIILAIQE KRDSNFIGQT DLLMLKNFAN QRYLQDMQRE
RLADINQIGK SDPNTEIAEW DKHYSGQTGE QLQQRLLDKN LNINSWLDVL LENRKGLLIS
ENNYGLDFVT RHLIGLKSKG ITTIGLGVLN AKFAQPLIDD YLRTGNLSGE LAVMVETNGL
GKLFESAFAK KMKIIALGVD SRRKGIEEDD YENIYRIDKT NQGVVEAFNQ PGGKFVAILS
SEFLQSQPGI EGPLSGITHR LGLPALTANE SGFTWLADNI YQRKAYQPLS LNSIEQSASF
PHFSVTADPG YQNILSTLDE LHARVSNSGK INTACQLHQE IQQYIQRNPD SELNSRLITL
KKQIAALFPS VELPFSPGRG QKRKMPSAIF DSHGSREGNT
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