ID G2N9I1_STREK Unreviewed; 279 AA.
AC G2N9I1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=tRNA/rRNA methyltransferase (SpoU) {ECO:0000313|EMBL:AEN08936.1};
GN ORFNames=SACTE_1009 {ECO:0000313|EMBL:AEN08936.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN08936.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN08936.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN08936.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002993; AEN08936.1; -; Genomic_DNA.
DR RefSeq; WP_014044925.1; NC_015953.1.
DR AlphaFoldDB; G2N9I1; -.
DR STRING; 862751.SACTE_1009; -.
DR KEGG; ssx:SACTE_1009; -.
DR PATRIC; fig|862751.12.peg.1062; -.
DR eggNOG; COG0566; Bacteria.
DR HOGENOM; CLU_021322_3_1_11; -.
DR OrthoDB; 9794400at2; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18095; SpoU-like_rRNA-MTase; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR PANTHER; PTHR43191:SF16; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR43191; RRNA METHYLTRANSFERASE 3; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:AEN08936.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001397};
KW Transferase {ECO:0000313|EMBL:AEN08936.1}.
FT DOMAIN 33..112
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
SQ SEQUENCE 279 AA; 28896 MW; 8525E2B5E39C727F CRC64;
MGTPELISAR SPRVAAARRL ARRNFRGKER RFIAEGPQAV REAAAHRGSD GTSTLTELFA
TVEAADRYAD IVGAAHAAGA RVHLADADVL ADVSQTVTPQ GLIGVCRFLD SPFEEILAAK
PTLVAVLAHV RDPGNAGTVL RCADAAGADA VVLTDASVDL YNPKSVRASV GSLFHLPVAV
GVPVEQAVQG LRGAGVRILA ADGAGTDDLD DELDAGTMGG PTAWVFGNEA WGLPEETRAL
ADAVVRVPIH GKAESLNLAT AAAVCLYASA RAQRPRRTG
//
