ID G2N9L2_STREK Unreviewed; 879 AA.
AC G2N9L2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Substrate-binding region of ABC-type glycine betaine transport system {ECO:0000313|EMBL:AEN08967.1};
GN ORFNames=SACTE_1041 {ECO:0000313|EMBL:AEN08967.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN08967.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN08967.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN08967.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363032};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363032}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. {ECO:0000256|RuleBase:RU363032}.
CC -!- SIMILARITY: In the C-terminal section; belongs to the OsmX family.
CC {ECO:0000256|ARBA:ARBA00035642}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the binding-protein-
CC dependent transport system permease family.
CC {ECO:0000256|ARBA:ARBA00035652}.
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DR EMBL; CP002993; AEN08967.1; -; Genomic_DNA.
DR RefSeq; WP_014044956.1; NC_015953.1.
DR AlphaFoldDB; G2N9L2; -.
DR STRING; 862751.SACTE_1041; -.
DR KEGG; ssx:SACTE_1041; -.
DR PATRIC; fig|862751.12.peg.1093; -.
DR eggNOG; COG2113; Bacteria.
DR eggNOG; COG4176; Bacteria.
DR HOGENOM; CLU_008673_0_1_11; -.
DR OrthoDB; 9787902at2; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR CDD; cd13639; PBP2_OpuAC_like; 2.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR007210; ABC_Gly_betaine_transp_sub-bd.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR47737; GLYCINE BETAINE/PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR PANTHER; PTHR47737:SF1; GLYCINE BETAINE_PROLINE BETAINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR Pfam; PF04069; OpuAC; 2.
DR SUPFAM; SSF161098; MetI-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 2.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363032};
KW Reference proteome {ECO:0000313|Proteomes:UP000001397};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363032};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363032};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363032}.
FT TRANSMEM 49..78
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 90..114
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 134..160
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 201..223
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 243..262
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT TRANSMEM 299..320
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363032"
FT DOMAIN 87..266
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50928"
SQ SEQUENCE 879 AA; 94987 MW; 51ADECDA0D491EB3 CRC64;
MPRFSFGEWV EDAVDWLQSN LTWIFDAIKT VLGGMYDGVN AVLGGGEPLL MAAIFAVLAF
WLRGIIPAVL TFAGFALIDS LALWDEAMAT LSLVIVAAVI TIVIAVPMGI WAARNSKVSA
TLRPVLDVMQ TMPAFVYLIP GVMFFGVGVT PGVIATIVFA MPPGVRMTEL GIRQVDGELV
EAAEAFGTTP KHTLTRVQLP LALPTIMAGI NQVIMLALSM VVIGGMAGAG GLGEKVYAAI
TQLQVGLAAE SGIAVVILAM YLDRMTGALN ERVSPLGRRA AAKAAAGARR MKFAHYKPGT
AVAMVGVVVL ALVAGGLNIA GSSDDSKGSQ AAAGDVGKGQ KINMGYIPWD EGIASTFLWK
EILEQRGFDT GVTQLDAGPL YSGVARGDID FQTDAWLPTT HKDYWDKYSD QLEDYGSWYG
PTSLELTVPS YVKGIDSLED LKGQGKKFNG KIIGIEASAG MMGTLNKQVL KEYGLEGEYE
VVSSSTSSML AELNASIKKK EPVVVTLWSP HWAYGAHDLK KLKDPKGAWG KGEEVHTVAH
KGFAEKSPVV ADWLKNFELT EKQLTGLENK IQEAGQGKEQ DGVRAWLKEN PDVVDKAAPL
PAGSDGGRPA QGKDAGKTVN MGYFPWDEAI ASTYLWQNML EDRGYKTTVK QLDPGPLYTG
LAQGQLDVQF DSWLPTTHKD YWNRYKDNLT DLGSWYGPTS LELTVPSYVK GIDSLEDLKG
QGKKFNGKII GIESSAGMMG TLNKQVLKAY GLEGEYEVVS SSTSSMLAEL NRSIKKKEPV
VVTLWSPHWA YGAHDLKKLE DPKGAWGEGE QIHTVAKKDF AKDFPELTGW LKDFKLSEDQ
LASLEVELQK GGAGKEKESA RHWMDAHPDV VEQLTPVTG
//
