ID G2NI55_STREK Unreviewed; 505 AA.
AC G2NI55;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Methyltransferase small {ECO:0000313|EMBL:AEN10864.1};
GN ORFNames=SACTE_2994 {ECO:0000313|EMBL:AEN10864.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN10864.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN10864.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN10864.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
CC -!- SIMILARITY: Belongs to the eukaryotic/archaeal PrmC-related family.
CC {ECO:0000256|ARBA:ARBA00006149}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002993; AEN10864.1; -; Genomic_DNA.
DR RefSeq; WP_014046847.1; NC_015953.1.
DR AlphaFoldDB; G2NI55; -.
DR STRING; 862751.SACTE_2994; -.
DR KEGG; ssx:SACTE_2994; -.
DR PATRIC; fig|862751.12.peg.3113; -.
DR eggNOG; COG2890; Bacteria.
DR HOGENOM; CLU_022532_0_0_11; -.
DR OrthoDB; 129465at2; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:UniProt.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR007848; Small_mtfrase_dom.
DR PANTHER; PTHR45875; METHYLTRANSFERASE N6AMT1; 1.
DR PANTHER; PTHR45875:SF1; METHYLTRANSFERASE N6AMT1; 1.
DR Pfam; PF05175; MTS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AEN10864.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001397};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AEN10864.1}.
FT DOMAIN 158..274
FT /note="Methyltransferase small"
FT /evidence="ECO:0000259|Pfam:PF05175"
SQ SEQUENCE 505 AA; 54009 MW; BE01F49D92D73D15 CRC64;
MSSLPASARA PRLREALLAA DFTADGLLER LGASAYAALA RSETVPALRA TRGDSPLDTL
VRLFLLQRSV PAALAAAALP LEECVEDGWL AREGDLIRAA VDVRPYGGPE GQDWFIVSDL
GCAVGGAGGI GSHEEGVVLG VGGASTTLAG ITVRRPVASA LDLGTGSGIQ ALHAAQHATQ
VTATDVNPRA LDFTRLTLAL SGAAPADLRE GSLFEPVGDL TYDLIVSNPP FVISPGARLT
YRDGGMGGDD LCRTLVQQAG DRLNDGGYAQ FLANWQHVEG EEWQDRVRAW VPEGCDAWIV
QREVQDVTQY TELWLRDSGD HRMDPAAYTE RYEAWLDEFE ARSTKAVGFG WITLRKSVAA
AAGNPSVVAE EWPHSVEQPL GSAVEAHFAR QDYLREHDDA ALLAAHFTLA EEVVQEQVGL
PGAEDPEHVV LRQHRGMRRA TKVDSVGAGF AGVCDGSLPA GRILDAIAQL MAEDPVLLRD
RTPQAIRLLV EEGFIEPVLG GARER
//
