ID G2NRB2_STREK Unreviewed; 358 AA.
AC G2NRB2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:AEN13254.1};
DE EC=4.6.1.1 {ECO:0000313|EMBL:AEN13254.1};
GN ORFNames=SACTE_5445 {ECO:0000313|EMBL:AEN13254.1};
OS Streptomyces sp. (strain SirexAA-E / ActE).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=862751 {ECO:0000313|EMBL:AEN13254.1, ECO:0000313|Proteomes:UP000001397};
RN [1] {ECO:0000313|EMBL:AEN13254.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Davenport K., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Adams A., Raffa K.,
RA Adams S., Book A., Currie C., Woyke T.;
RT "Complete sequence of Streptomyces sp. SirexAA-E.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEN13254.1, ECO:0000313|Proteomes:UP000001397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SirexAA-E / ActE {ECO:0000313|Proteomes:UP000001397};
RX PubMed=24710170; DOI=10.1371/journal.pone.0094166;
RA Takasuka T.E., Acheson J.F., Bianchetti C.M., Prom B.M., Bergeman L.F.,
RA Book A.J., Currie C.R., Fox B.G.;
RT "Biochemical properties and atomic resolution structure of a
RT proteolytically processed beta-mannanase from cellulolytic Streptomyces sp.
RT SirexAA-E.";
RL PLoS ONE 9:e94166-E94166(2014).
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DR EMBL; CP002993; AEN13254.1; -; Genomic_DNA.
DR RefSeq; WP_014049204.1; NC_015953.1.
DR AlphaFoldDB; G2NRB2; -.
DR STRING; 862751.SACTE_5445; -.
DR KEGG; ssx:SACTE_5445; -.
DR PATRIC; fig|862751.12.peg.5653; -.
DR eggNOG; COG2114; Bacteria.
DR HOGENOM; CLU_043761_2_0_11; -.
DR OrthoDB; 310836at2; -.
DR Proteomes; UP000001397; Chromosome.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR032026; Ad_Cy_reg.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR Pfam; PF16701; Ad_Cy_reg; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:AEN13254.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001397}.
FT DOMAIN 195..304
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 358 AA; 38036 MW; D56BC09D56E5D043 CRC64;
MNAPDQEPRS GAGEPRPTVE EVLLGGGRVH TRRDVVARTG VTAERTAQIW HALGFPVVDD
DARVFTDADV DALRAGERLI EAGLITAESE TMMARALGHH LSRLAEWQVS TLWAWMSRGP
GVPGHGGEPV DHAAALLPEM ERLQRHVWRR HLAAHAGRMA AEGQGFVPAG PGRPVGAAAD
GPTAAGEGTD VRELAVGFTD MVGYTRMTRG LDTAELGRVL DRFESLTGDV VAEGGGRVVK
TIGDEVLFVC DSASASAGIA LELTARVEEE KRLPKVRTGL AHGAVLIRFG DVYGGAVNVA
ARLTGVARPA TVLVDTAFAG ELAGTAAYEL RALRPVSVRG YNRLRPVVLR PRRRTGAR
//
