ID G2SZR3_ROSHA Unreviewed; 352 AA.
AC G2SZR3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:AEN95397.1};
GN OrderedLocusNames=RHOM_01375 {ECO:0000313|EMBL:AEN95397.1};
OS Roseburia hominis (strain DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=585394 {ECO:0000313|EMBL:AEN95397.1, ECO:0000313|Proteomes:UP000008178};
RN [1] {ECO:0000313|EMBL:AEN95397.1, ECO:0000313|Proteomes:UP000008178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183
RC {ECO:0000313|Proteomes:UP000008178};
RX PubMed=26543119; DOI=10.1128/genomeA.01286-15;
RA Travis A.J., Kelly D., Flint H.J., Aminov R.I.;
RT "Complete genome sequence of the human gut symbiont Roseburia hominis.";
RL Genome Announc. 3:E0128615-E0128615(2015).
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DR EMBL; CP003040; AEN95397.1; -; Genomic_DNA.
DR RefSeq; WP_014078491.1; NC_015977.1.
DR AlphaFoldDB; G2SZR3; -.
DR STRING; 585394.RHOM_01375; -.
DR GeneID; 77457928; -.
DR KEGG; rho:RHOM_01375; -.
DR eggNOG; COG2206; Bacteria.
DR HOGENOM; CLU_000445_92_1_9; -.
DR OrthoDB; 9804747at2; -.
DR BioCyc; RHOM585394:G1H02-270-MONOMER; -.
DR Proteomes; UP000008178; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR PANTHER; PTHR43155:SF9; METAL DEPENDENT PHOSPHOHYDROLASE-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AEN95397.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008178}.
FT DOMAIN 107..304
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 352 AA; 39787 MW; 407B31CC8B21DC24 CRC64;
MRYLPTSRLT PGMALGQDIY DGAGRLLLGR HILLTEEQIS NLEFLGFPGV YVDDEFSRGI
EIQQIVSPEV RRQALKIVYD LFHTDMRKQE PSEAEFKLRK TVESVVDDVI CNGDIMCNIM
DIKSYDDYIY YHSIHVGILS VVVGARLGLP HDELCQLAAA ALLHDIGKRF IDHDIVRGGK
AHRSEKEQEV YRSHPKIGAE YLRETCRFSA DVYEGIMEHH ECYNGEGYPL GKKGGEIHLF
ARIIRIADCY DAKVSAFPAQ KSLSPSEALE YVMALGDRWF DPDIVAVFAR KVAAYPIGCE
VELSNGQHAV VARNFENFPL RPLVRVVETG EMLNMRDDEK ARAVTVGRLI VR
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