ID   G2T068_ROSHA            Unreviewed;       562 AA.
AC   G2T068;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Secretion protein HlyD family protein {ECO:0000313|EMBL:AEN95863.1};
GN   OrderedLocusNames=RHOM_03705 {ECO:0000313|EMBL:AEN95863.1};
OS   Roseburia hominis (strain DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183).
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=585394 {ECO:0000313|EMBL:AEN95863.1, ECO:0000313|Proteomes:UP000008178};
RN   [1] {ECO:0000313|EMBL:AEN95863.1, ECO:0000313|Proteomes:UP000008178}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16839 / JCM 17582 / NCIMB 14029 / A2-183
RC   {ECO:0000313|Proteomes:UP000008178};
RX   PubMed=26543119; DOI=10.1128/genomeA.01286-15;
RA   Travis A.J., Kelly D., Flint H.J., Aminov R.I.;
RT   "Complete genome sequence of the human gut symbiont Roseburia hominis.";
RL   Genome Announc. 3:E0128615-E0128615(2015).
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DR   EMBL; CP003040; AEN95863.1; -; Genomic_DNA.
DR   AlphaFoldDB; G2T068; -.
DR   STRING; 585394.RHOM_03705; -.
DR   KEGG; rho:RHOM_03705; -.
DR   eggNOG; COG0845; Bacteria.
DR   HOGENOM; CLU_589092_0_0_9; -.
DR   Proteomes; UP000008178; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR   Pfam; PF13437; HlyD_3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008178};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        27..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          55..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          532..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          187..239
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          313..411
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        532..549
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   562 AA;  59534 MW;  8B586EE21D530BE0 CRC64;
     MKCRKGKDET MKIAWVHKLL GKHSKKFYGI LAGILTAAVA GSGVGYHVIA ASGTADQTEE
     DTQIDETDGQ EDGSFSGTGT TQVKTESQLP DFSVNAVTMT VEEVYVEAGS TVAEGDALFK
     IDDESMADAK AYYEDAISDA ETALQSAQIN FENGVLEAES ELSSTKLAAD TAQDTYDAAV
     SELSVKTSEA QEAYDEAVEE ISDYQDAIDN GTYYTQVGIN EKQAAVDTAQ ATLTEKQTQL
     SDAQSSSQVA KDAYAADMAN MKTQIEAGAS HTDLAALADQ LAADYTAVQE AADALSQSQT
     EAESANSALQ LANQTFQKAV EEYNTKVTEA NEKIAELTDE LEELSDACDE AERNEMTAQP
     ALLQQYEEAV LEGKNADTEY EASLENLQSA VDEAQDTLDE LKEQQSALLA IEDGVVCADR
     DGTLASVTYE AGDTLIKNTA FASYYDLDTI LISVEVSQNN IAKLAVGDTV QVQISGSRMG
     AIDGTVYSIA SEKTSGGSMS NVTYAVIVAV DNTDGTLTTG VQATVKFETQ ATGATEMEET
     KTAGKTETIG ASETEEAGGK TE
//