ID G2WQB7_VERDV Unreviewed; 179 AA.
AC G2WQB7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Phosphatidylglycerol/phosphatidylinositol transfer protein {ECO:0000256|ARBA:ARBA00016056};
GN ORFNames=VDAG_00559 {ECO:0000313|EMBL:EGY13877.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY13877.1, ECO:0000313|Proteomes:UP000001611};
RN [1] {ECO:0000313|Proteomes:UP000001611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC {ECO:0000313|Proteomes:UP000001611};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- FUNCTION: Catalyzes the intermembrane transfer of phosphatidylglycerol
CC and phosphatidylinositol. {ECO:0000256|ARBA:ARBA00002053}.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SIMILARITY: Belongs to the NPC2 family.
CC {ECO:0000256|ARBA:ARBA00006370}.
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DR EMBL; DS572695; EGY13877.1; -; Genomic_DNA.
DR RefSeq; XP_009650231.1; XM_009651936.1.
DR AlphaFoldDB; G2WQB7; -.
DR STRING; 498257.G2WQB7; -.
DR EnsemblFungi; EGY13877; EGY13877; VDAG_00559.
DR GeneID; 20702022; -.
DR KEGG; vda:VDAG_00559; -.
DR eggNOG; KOG4680; Eukaryota.
DR HOGENOM; CLU_097982_0_0_1; -.
DR InParanoid; G2WQB7; -.
DR OMA; QTYDLCE; -.
DR OrthoDB; 5472305at2759; -.
DR Proteomes; UP000001611; Chromosome 2.
DR GO; GO:0000328; C:fungal-type vacuole lumen; IEA:EnsemblFungi.
DR GO; GO:0032934; F:sterol binding; IEA:EnsemblFungi.
DR GO; GO:0032366; P:intracellular sterol transport; IEA:EnsemblFungi.
DR CDD; cd00917; PG-PI_TP; 1.
DR Gene3D; 2.60.40.770; -; 1.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR003172; ML_dom.
DR InterPro; IPR033917; ML_PG-PI_TP.
DR InterPro; IPR039670; NPC2-like.
DR PANTHER; PTHR11306; NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED; 1.
DR PANTHER; PTHR11306:SF0; PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN; 1.
DR Pfam; PF02221; E1_DerP2_DerF2; 1.
DR SMART; SM00737; ML; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000001611};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transport {ECO:0000256|ARBA:ARBA00023055}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..179
FT /note="Phosphatidylglycerol/phosphatidylinositol transfer
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003438871"
FT DOMAIN 45..167
FT /note="MD-2-related lipid-recognition"
FT /evidence="ECO:0000259|SMART:SM00737"
SQ SEQUENCE 179 AA; 19285 MW; 630BDEFD472BE7C4 CRC64;
MRFTSAILAV LSVGLVPASA RSVLVERDQS IITGDDRKIP GDSPLELCDK DHGKDIVHIK
KVDLSPNPPK AGEDLVITAS GTVDEDIEEG AYVLLQVKYG LIRLISTKAD FCEQVGEVDL
ECPIKKGDLA LTKTVKLPAE IPPGKYTVFA DLYTKDDEPI TCLTASVAFS RGSLLGFEL
//
