ID G2WSV3_VERDV Unreviewed; 669 AA.
AC G2WSV3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Sugar transporter {ECO:0000313|EMBL:EGY17194.1};
GN ORFNames=VDAG_00876 {ECO:0000313|EMBL:EGY17194.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY17194.1, ECO:0000313|Proteomes:UP000001611};
RN [1] {ECO:0000313|Proteomes:UP000001611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC {ECO:0000313|Proteomes:UP000001611};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
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DR EMBL; DS572696; EGY17194.1; -; Genomic_DNA.
DR RefSeq; XP_009648057.1; XM_009649762.1.
DR AlphaFoldDB; G2WSV3; -.
DR STRING; 498257.G2WSV3; -.
DR EnsemblFungi; EGY17194; EGY17194; VDAG_00876.
DR GeneID; 20702339; -.
DR KEGG; vda:VDAG_00876; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_001265_43_4_1; -.
DR InParanoid; G2WSV3; -.
DR OMA; TAVGFWR; -.
DR OrthoDB; 1751031at2759; -.
DR Proteomes; UP000001611; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0015798; P:myo-inositol transport; IEA:UniProt.
DR GO; GO:0015791; P:polyol transmembrane transport; IEA:UniProt.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003663; Sugar/inositol_transpt.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR48020:SF12; MFS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48020; PROTON MYO-INOSITOL COTRANSPORTER; 1.
DR Pfam; PF00083; Sugar_tr; 1.
DR PRINTS; PR00171; SUGRTRNSPORT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001611};
KW Sugar transport {ECO:0000313|EMBL:EGY17194.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:EGY17194.1}.
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 492..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..576
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 113..580
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 669 AA; 73429 MW; 752410747D3910CE CRC64;
MSTPLSDVHP ASRPAPRRQS HAQTFHDNPL GQLSDAQLEE DARRFVREFL FVDVKNLIRG
MLVAKDPRLY EVAARSSDPE ASHGLPVKLS DDEKKALRRE RDVPLGERGV WTIIATVSLA
AFLQGHVQSS FNGGALYDGV FGLHTIGDRE DADVSSTLSN FTGDDWKLGA ANASPFLFAA
LLGCPLALPV NHYLGRKGGV AIAAFLIFAT SIASAFATTW YHLFGIRLVN GIGMGLKAVS
TPILASETAV GLWRGTSILA WQLWVACGIA IGFAFNLVFS TAKTDKITFA LIMAAPAVPS
LALFILVIWF CDESPRYLLR KSSPNYNPKR AYEIIRKLRS TELQALRDIY LLQKSIDRGE
PLVSAPRKTS MSETFVNFVR QYQQLLRVRR LRNALVSSSI VNLSQQLCGI NVLAFYSGTL
FSRAGTNRAT AMQYSLGIGA VNFVFCLPAI RTIDTLGRRK WLNLTLPLMA AFMAAAALSF
KAPDGAKVPL VTVWLFLFAA AYSPGLGPIP FTYASESFPL SHREAGAAFA IAVNLGFAGL
LSMFYPRINS SLKDAGALGL FSGLNVVAFV LVFFLLEETK RRSLEDLDTV FEHSKRDFAR
HQAARVAWFF RRWVLGKREA KPSIGYLEGD GRKPGAEAAS RTLGGTQGEV VEVENSEATR
REEIGDLYW
//
