ID G2WWQ0_VERDV Unreviewed; 312 AA.
AC G2WWQ0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase {ECO:0000313|EMBL:EGY20020.1};
GN ORFNames=VDAG_02036 {ECO:0000313|EMBL:EGY20020.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY20020.1, ECO:0000313|Proteomes:UP000001611};
RN [1] {ECO:0000313|Proteomes:UP000001611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC {ECO:0000313|Proteomes:UP000001611};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC family. {ECO:0000256|ARBA:ARBA00006484}.
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DR EMBL; DS572697; EGY20020.1; -; Genomic_DNA.
DR RefSeq; XP_009656360.1; XM_009658065.1.
DR AlphaFoldDB; G2WWQ0; -.
DR EnsemblFungi; EGY20020; EGY20020; VDAG_02036.
DR GeneID; 20703499; -.
DR KEGG; vda:VDAG_02036; -.
DR eggNOG; KOG0725; Eukaryota.
DR HOGENOM; CLU_010194_1_0_1; -.
DR InParanoid; G2WWQ0; -.
DR OMA; SIAQTCA; -.
DR OrthoDB; 1356677at2759; -.
DR Proteomes; UP000001611; Chromosome 7.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR CDD; cd05233; SDR_c; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR InterPro; IPR002347; SDR_fam.
DR PANTHER; PTHR43180; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210); 1.
DR PANTHER; PTHR43180:SF66; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (AFU_ORTHOLOGUE AFUA_6G11210)-RELATED; 1.
DR Pfam; PF13561; adh_short_C2; 1.
DR PRINTS; PR00081; GDHRDH.
DR PRINTS; PR00080; SDRFAMILY.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00061; ADH_SHORT; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001611}.
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 32081 MW; 4C6F0D310FCF7E78 CRC64;
MPPSAKDRIS ALGHQLAPSS ASSTTSLPAI TKVAGPSAAP RVAGKVVVIT GTNSPLGIGR
AAAHQFAENG ARALYLCDFD GTHLDAHAAE IRAAHPAVEV HVRRFDAAEE QAVRDVVAHA
VTTYGRLDVF FANAGIVGPM ALFTDVTETD FMQMMRTNVL SVFLAAKHAA PAMQLTSSAK
PQAGGSIIGT ASVAGIRSNA GTTPYSAAKA AVISVAQTTS YQLAGTGVRV NAICPGLIET
GMTADVYEAA RARGTEKRIG QLNPLKRGGH ADEIARVALF LGSDESSYVN GQAWAVDGGL
SAGHPYVPGR IG
//
