ID G2WZ31_VERDV Unreviewed; 298 AA.
AC G2WZ31;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=GPN-loop GTPase 3 {ECO:0000256|ARBA:ARBA00014587, ECO:0000256|RuleBase:RU365059};
GN ORFNames=VDAG_03273 {ECO:0000313|EMBL:EGY21833.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY21833.1, ECO:0000313|Proteomes:UP000001611};
RN [1] {ECO:0000313|Proteomes:UP000001611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC {ECO:0000313|Proteomes:UP000001611};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- FUNCTION: Small GTPase required for proper nuclear import of RNA
CC polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly
CC step prior to nuclear import. {ECO:0000256|RuleBase:RU365059}.
CC -!- SUBUNIT: Binds to RNA polymerase II (RNAPII).
CC {ECO:0000256|RuleBase:RU365059}.
CC -!- SIMILARITY: Belongs to the GPN-loop GTPase family.
CC {ECO:0000256|ARBA:ARBA00005290, ECO:0000256|RuleBase:RU365059}.
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DR EMBL; DS572699; EGY21833.1; -; Genomic_DNA.
DR RefSeq; XP_009655433.1; XM_009657138.1.
DR AlphaFoldDB; G2WZ31; -.
DR STRING; 498257.G2WZ31; -.
DR EnsemblFungi; EGY21833; EGY21833; VDAG_03273.
DR GeneID; 20704736; -.
DR KEGG; vda:VDAG_03273; -.
DR eggNOG; KOG1534; Eukaryota.
DR HOGENOM; CLU_037460_0_0_1; -.
DR InParanoid; G2WZ31; -.
DR OMA; CIQYHEA; -.
DR OrthoDB; 168004at2759; -.
DR Proteomes; UP000001611; Chromosome 6.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0007064; P:mitotic sister chromatid cohesion; IEA:EnsemblFungi.
DR GO; GO:0006606; P:protein import into nucleus; IEA:EnsemblFungi.
DR CDD; cd17872; GPN3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004130; Gpn.
DR InterPro; IPR030228; Gpn3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR21231:SF7; GPN-LOOP GTPASE 3; 1.
DR PANTHER; PTHR21231; XPA-BINDING PROTEIN 1-RELATED; 1.
DR Pfam; PF03029; ATP_bind_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|RuleBase:RU365059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU365059};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU365059};
KW Reference proteome {ECO:0000313|Proteomes:UP000001611}.
FT REGION 201..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..226
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 298 AA; 33462 MW; 4A885A3077BD012D CRC64;
MSKFGVMVMG PAGAGKSTFC ASLITNLNLN RRSAFYVNLD PAAESFEHEP DLDIKDLISL
KDAMEEVGLG PNGGLIYCFE FLMENLDWLT EALDSLTEEY LIIIDMPGQI ELYTHIPILP
ALARFLGQTG SLDIRLCAAY LLEATFVVDR AKFFAGTLSA MSAMIMLEIP HINILSKMDL
VKDQVRKKDL KRFLTPDTTL LEDDPQGIGR EARPVDDDET GDPQDRDLIM RGTSFNRLNR
AVAGLIENFS MVNYLKLDSS DEDSVTSILS YIDDIIQYHE AQEPKEMKDE EFEEPQDD
//
