ID G2X745_VERDV Unreviewed; 615 AA.
AC G2X745;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 03-MAY-2023, entry version 38.
DE SubName: Full=Magnesium transporter ALR1 {ECO:0000313|EMBL:EGY14813.1};
GN ORFNames=VDAG_06303 {ECO:0000313|EMBL:EGY14813.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY14813.1, ECO:0000313|Proteomes:UP000001611};
RN [1] {ECO:0000313|Proteomes:UP000001611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC {ECO:0000313|Proteomes:UP000001611};
RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT "Comparative genomics yields insights into niche adaptation of plant
RT vascular wilt pathogens.";
RL PLoS Pathog. 7:E1002137-E1002137(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; DS572706; EGY14813.1; -; Genomic_DNA.
DR RefSeq; XP_009656976.1; XM_009658681.1.
DR AlphaFoldDB; G2X745; -.
DR EnsemblFungi; EGY14813; EGY14813; VDAG_06303.
DR GeneID; 20707766; -.
DR KEGG; vda:VDAG_06303; -.
DR eggNOG; ENOG502QPTQ; Eukaryota.
DR HOGENOM; CLU_007127_6_1_1; -.
DR InParanoid; G2X745; -.
DR OMA; CNENYQV; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000001611; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF55; MAGNESIUM TRANSPORTER ALR1-RELATED; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001611};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 588..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 234..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..83
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 615 AA; 69640 MW; 8AC839CBEC34DDB1 CRC64;
MSDHEENGSD VAFKTPIPEL DDHRHQPPSS QQHERVRRGT FDSLYGARLL AADDDRAPDN
TKNRVKGSEE AILDDEIDQA SPTARRPRRP TVETIGEQRS ISPPNSVKAF AEARRRERDM
SFSEPRPDDT ELHRAISIAS RRSRPRTVDD DAVSMDSNHT AEEDVCFPLQ DKGRKDQLYI
DFDYLENFLQ SESAARALSK QETVDRSFAD LRPQNSTCAP DGIQLATLDG DILDMPSESS
MVDDNKEKPT LADESKAPQQ PPIDKNRFSF FSSAWESTIH AQDFGDLVLP GEDVRGLFAL
PPNESDGVWW LNVNNPTKEE VQAICKAFGI HPLTIEDITT QEAREKIELF PSYYFASFRS
FQTVEEDDGQ EYEPFNIYVV VFREGTLSFS FQPNAHASHV RKRIALLKDY VALSSDWICY
AMIDDIVDCF APIIRKIELE ADSIEDEVFV IREGDSSVFL RSIGRVRKNC MALMRLLGGK
ADVLRGFTKR CNENYKVTPR MDIGLYLGDI QDHVVTMVTN LGHFEKILSR SHSNYLAQLS
INNIAQGTDT NRVLSKITFL ASILVPMNLV SGLFGMNVRV PFQDGPNVIP FFTIMGSLFF
FCIVILVWAR RARYI
//
