ID   G2X9U4_VERDV            Unreviewed;       431 AA.
AC   G2X9U4;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Carnosine N-methyltransferase {ECO:0000256|ARBA:ARBA00015448};
DE            EC=2.1.1.22 {ECO:0000256|ARBA:ARBA00012003};
GN   ORFNames=VDAG_07139 {ECO:0000313|EMBL:EGY15975.1};
OS   Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS   (Verticillium wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX   NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY15975.1, ECO:0000313|Proteomes:UP000001611};
RN   [1] {ECO:0000313|Proteomes:UP000001611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137
RC   {ECO:0000313|Proteomes:UP000001611};
RX   PubMed=21829347; DOI=10.1371/journal.ppat.1002137;
RA   Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E.,
RA   Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J.,
RA   Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., Santhanam P.,
RA   Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., Inderbitzin P.,
RA   Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., Galagan J.,
RA   Cuomo C.A., Dobinson K.F., Ma L.-J.;
RT   "Comparative genomics yields insights into niche adaptation of plant
RT   vascular wilt pathogens.";
RL   PLoS Pathog. 7:E1002137-E1002137(2011).
CC   -!- SIMILARITY: Belongs to the carnosine N-methyltransferase family.
CC       {ECO:0000256|ARBA:ARBA00010086}.
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DR   EMBL; DS572709; EGY15975.1; -; Genomic_DNA.
DR   RefSeq; XP_009654339.1; XM_009656044.1.
DR   AlphaFoldDB; G2X9U4; -.
DR   EnsemblFungi; EGY15975; EGY15975; VDAG_07139.
DR   GeneID; 20708602; -.
DR   KEGG; vda:VDAG_07139; -.
DR   eggNOG; KOG2798; Eukaryota.
DR   HOGENOM; CLU_030612_2_0_1; -.
DR   InParanoid; G2X9U4; -.
DR   OMA; LWTGGGQ; -.
DR   OrthoDB; 2721776at2759; -.
DR   Proteomes; UP000001611; Chromosome 5.
DR   GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR012901; CARME.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12303:SF6; CARNOSINE N-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12303; UNCHARACTERIZED; 1.
DR   Pfam; PF07942; CARME; 1.
DR   SMART; SM01296; N2227; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001611};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..431
FT                   /note="Carnosine N-methyltransferase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003439778"
SQ   SEQUENCE   431 AA;  48471 MW;  16DF829E1E88B768 CRC64;
     MRLSATIPLA VLACAKAALA AEDIAKGDTP IDIHEDLAAV IVTLTEEFKP SPRYEAEHKA
     LLKRMSKSHG KWDTTHPRAR LLDALHGYVR YRERQTAELD KWRRMYKNTS SSQKKVLEHA
     VGYTKKMDTI ASLIEQNHVL CQQIVDGALE FYGVERDEMT RYIEAKEKEN KAAERVSVSQ
     ALKHYVRDWT VSGLRERDAA FPCIIQSLEQ YFPDRSQGDV KVLLPGAGVG RLGHEVAALG
     GFEVTTNEWS MYMNLAYRFL EKHPRVGSNN VHPFIDGWSH HASTADMFRG VAFPDRPVNA
     SAVVLVEGDF TTAFKGQNGH FDALVTHFFI DTARNLMSYF ETIHGLLRKG GIWVNLGPLL
     YGTGPYVQLS LDEIIAVVNA MGFEFVDAPE SCGELTFADE KVRGREAVYG FNERALVKNA
     YNAQSWVMRK K
//