ID G2XDF9_VERDV Unreviewed; 1511 AA.
AC G2XDF9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Brefeldin A resistance protein {ECO:0000313|EMBL:EGY17027.1};
GN ORFNames=VDAG_08191 {ECO:0000313|EMBL:EGY17027.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY17027.1};
RN [1] {ECO:0000313|EMBL:EGY17027.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VdLs.17 {ECO:0000313|EMBL:EGY17027.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J.J., Klosterman S.J., Subbarao K., Dobinson K., Veronese P.,
RA Kang S., Gold S.E., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Verticillium dahliae VdLs.17.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; DS572713; EGY17027.1; -; Genomic_DNA.
DR RefSeq; XP_009655863.1; XM_009657568.1.
DR EnsemblFungi; EGY17027; EGY17027; VDAG_08191.
DR GeneID; 20709654; -.
DR KEGG; vda:VDAG_08191; -.
DR eggNOG; KOG0065; Eukaryota.
DR HOGENOM; CLU_000604_35_0_1; -.
DR InParanoid; G2XDF9; -.
DR OMA; FCISNWA; -.
DR OrthoDB; 5473955at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241:SF298; ABC MULTIDRUG TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 491..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 525..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 570..593
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 636..655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..764
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1143..1163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1175..1195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1216..1244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1256..1277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1289..1308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1452..1474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..379
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 811..1049
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1511 AA; 167652 MW; 2F9C6B63C9670CA6 CRC64;
MDDKRRVPDG TWGEHAPGDV SVSAAMSEYH DLNRELTHRS RRTTTNHSAD RNSDSTRCPE
DDGDETDFDL PDFLRQGILD PRTPTGGPTK RLGISFRNLT VRAPAANSAP LKTLPRAILN
TFGPDLWSLI STRLPSSLKS GKASDPETVP LIHDMTGAVR PGEILLVLGR PGSGCSTLLK
TLANHRAEYS AVDGEVYYGP LPAAEQEARF RGEVVYCEED DRHFPTLTVW QTLWFALATK
TRRRAAWTVP VVLDAFLAMF GIDHTRDTLV GDEHVRGVSG GERKRVSLAE TLATRASVVC
WDNSTRGLDA STALSFAKSL RVYTDVGGRT TLVTLYQAGE SIYELMDKVL VIDEGRMLFH
GRAEEAQAYF EGLGYWRPPR QTTADFLTSI ADRNARHFQE GREATAPKTP EALEAAFRAS
EHYQRLLEDV DLYDREHRAA SDPDEKHKRF EDAVQGAKSK HVKDESPYTV SVPRQIAAAT
RRQAWLFWGD LGTFYTKLAI IVVNALIVGS LFYESESGAT SAAFSMSSAM FFSVAFIGWL
EFAVLAPAIM GRATIERQRQ FALYRPSAVV LARAVLDLPL IFIMVVVFSL PFYFLAKFDV
EAGKFFVYML LVYVATLCLT TMYRMFAALS STVDDAIRFV SVFLNIMFIL TGYVIPRSTL
MSDSPWFGWF SYANPVAYGY EALLGNEFGG RELRCSESNL VPRGPGADAD YQGCTLPGST
FGSSTVSGEA YLQTSFDFSR SNLWRNFGIM LAFTAFFLLV NVWAVEKVRF TGSSAHSLVF
AKPSETKEET SAEQQKADET LDKIGDGTSV FTFKDIRYTV PYGTGHRRLL NGVNGYAAPG
KMVALMGSSG AGKTTLLNTL AQRQRIGVVS GDILVNGVVP GAAFKRGTGF CEQRDIHEGS
STVREALDFS ALLRQEKHIP KAEKLAYVDR IVRLLELDGL SHALISSLTV EQRKRVTIGV
ELAARPSLLL FLDEPTSGLD SQSAFSIVRF LRRLADAGQA IMCTIHQPSS DLIEQFDMIL
ALNRGGNTFY FGPVGENGSV VIDYFARRGF PCPPSRNVAE FILETASRPS TNSEGVRVDW
DVEWLVSEEN RGVIDYINRV TAERRHEAPS TEADAQFAAS TLEQCRLLIQ RTFIKQWREP
SYVYGRLFVH VVMGILNGFT FWQQGNDVAS LQNRMFTAII FAFFLPPAVV NSVVVNFFRH
RELWEDRELP SATYGWVAFC TANVVCELPM AVVSGTLYWL LWYLPVGFPA EASTSGHVYL
MTIMWSFFQT SWGQWIAALG PTYGMISNVL PFFFVMIALF NGIFTPYHSM PAFWKYWMYY
VNHSTWFSRG VLSAVVHATA GLQRHLHAVP SMPAFWKYWM YYVNPSTWFS RGVLSAVLPA
VAVRCAPAEL ARFDPPPGST CGDYAGGFVA SVAGAGYLED PSATSDCGFC PYNDGGEYMA
GLNVRAGDKW PAFGIMVAFA VANWALVYLF VYAFRVRGWT FGLGGLSGRV AAVKARVVRG
RGQEGEEKSE A
//
