ID G2XIL8_VERDV Unreviewed; 1078 AA.
AC G2XIL8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 03-MAY-2023, entry version 54.
DE SubName: Full=Exportin-1 {ECO:0000313|EMBL:EGY20371.1};
GN ORFNames=VDAG_10000 {ECO:0000313|EMBL:EGY20371.1};
OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137)
OS (Verticillium wilt).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Plectosphaerellaceae; Verticillium.
OX NCBI_TaxID=498257 {ECO:0000313|EMBL:EGY20371.1};
RN [1] {ECO:0000313|EMBL:EGY20371.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VdLs.17 {ECO:0000313|EMBL:EGY20371.1};
RG The Broad Institute Genome Sequencing Platform;
RA Ma L.-J.J., Klosterman S.J., Subbarao K., Dobinson K., Veronese P.,
RA Kang S., Gold S.E., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D.,
RA Hepburn T., Sykes S., Alvarado L., Kodira C.D., Lander E., Galagan J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Verticillium dahliae VdLs.17.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; DS572724; EGY20371.1; -; Genomic_DNA.
DR RefSeq; XP_009654052.1; XM_009655757.1.
DR AlphaFoldDB; G2XIL8; -.
DR STRING; 498257.G2XIL8; -.
DR EnsemblFungi; EGY20371; EGY20371; VDAG_10000.
DR GeneID; 20711463; -.
DR KEGG; vda:VDAG_10000; -.
DR eggNOG; KOG2020; Eukaryota.
DR HOGENOM; CLU_011906_0_0_1; -.
DR InParanoid; G2XIL8; -.
DR OMA; WAFKHNN; -.
DR OrthoDB; 169519at2759; -.
DR GO; GO:0000776; C:kinetochore; IEA:EnsemblFungi.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0005816; C:spindle pole body; IEA:EnsemblFungi.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:EnsemblFungi.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:EnsemblFungi.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030619; F:U1 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030620; F:U2 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030621; F:U4 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0030623; F:U5 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0017070; F:U6 snRNA binding; IEA:EnsemblFungi.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0006611; P:protein export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0034501; P:protein localization to kinetochore; IEA:EnsemblFungi.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:EnsemblFungi.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 26..92
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1078 AA; 123430 MW; B22DA661561287D2 CRC64;
MAITIPELDN LVRSFYEGRG EQQKQAQAAL NQFKEDQDSW LLVDNILSEA SYPQTKYLGL
QVLDSVIMTR WKVLPREQCQ GIRNFIVQFI LQVSGSEETM KAQKTLLNKL NLVLISILKQ
DWPHNWPTFI NEIISACHSS LSVCENNMVI LRLLSEEVFD YSAEQMTSTK TRNLKTTMCA
EFSQIFTLCQ EVLNSATQTS LVKATLETLL RFCNWIPLGY IFETNLIDTL RTRFLPEPEF
RNVTLQCLTE IGGLQTGGPG QPNSYDEQLV KMFTEVLSTI SNIVPITIDL KTTYPTSNSR
DQEFVQNMAL FLSNFFGMHL SLIENLPNRD YLAHGHFYLI RISQIEDREI FKICLDYWLK
LVNELYDEMQ QLPMTELNPL MGMGGGLSNA GAPNPALLAN YPLRKHKYGE VLSNLRQVMI
EKMVRPEEVL VVENDEGEIV REFVKESDTV QLYKTIRECL VYLTHLDVTD TENIMTEKLA
RQVDGTEWSW HNCNVLCWAI GSISLAMNEE TEKRFLVTVI KDLLGLTEMK RGKDNKAVVA
SNIMYIVGQY PRFLKAHWKF LKTVVNKLFE FMHESHEGVQ DMACDTFIKI ARQCRRHFVA
LQPSENEPFI EEIVRNMHKI TCDLTPQQIH TFYEACGYMV AAQGNKHQQE RLLSDLMAIP
NAAWDEVIKT ARANPTFLQD SETIKIIGNI MKTNVSACSS IGPYFYPQIG RIFHDMLQMY
QATSQLISEA VQNQGEIATK MPNVRGLRTI KKEILKLIET YVEKAEDLNA VRQQMVPPLL
ESILTDYNRN VAGARDAEVL KAISAIITKL SSLMEDQVPN IMENVFECTL EMINKDFSEF
PEHRVEFFNL LRAINLHCFP ALLKLDNRQF KFVIDSCSWA FKHDNRDVEA AGLNMCLELI
NNIAETDVQT SNAFFQQFFI TILQDVFFVL TDTDHKAGFK TQSMILMRMF YFVHPADGTS
PKIQGPIYPP DQAPGGTPNK EFLANFVAQL LKGAFPNLQP AQIESFVEGL FNLNTTYDKF
RLNLRDFLVS LKEFAGDNAE LFLIEKEQQE KDAKAADFER RGKVGGLLKP SELEDDEL
//
