ID G3AIN1_SPAPN Unreviewed; 562 AA.
AC G3AIN1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0000259|Pfam:PF00324};
GN ORFNames=SPAPADRAFT_48864 {ECO:0000313|EMBL:EGW33746.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW33746.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. YAT (TC 2.A.3.10) family. {ECO:0000256|ARBA:ARBA00006983}.
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DR EMBL; GL996500; EGW33746.1; -; Genomic_DNA.
DR RefSeq; XP_007373330.1; XM_007373268.1.
DR AlphaFoldDB; G3AIN1; -.
DR STRING; 619300.G3AIN1; -.
DR GeneID; 18871276; -.
DR KEGG; spaa:SPAPADRAFT_48864; -.
DR eggNOG; KOG1286; Eukaryota.
DR HOGENOM; CLU_007946_12_0_1; -.
DR InParanoid; G3AIN1; -.
DR OMA; PKFLDYV; -.
DR OrthoDB; 2024136at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IEA:UniProt.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR PANTHER; PTHR43341; AMINO ACID PERMEASE; 1.
DR PANTHER; PTHR43341:SF17; GENERAL AMINO ACID PERMEASE AGP1-RELATED; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 59..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 61..517
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 562 AA; 62315 MW; 0E65D9D25AA0E02F CRC64;
MTEPKKDILE FEKFDEGLHL QSTQTDSSVD KSFAQSIVDS FRRAPPNTSY KKAISKNELR
IMSLSTGLGT GLLVAAGQKL KNSGPAGLLI AYAVVGLGML VPTVRSLSEL SVAYSGLPGG
FQSYFAKFID ESLAFALGWN YAIQWMCVIS LELVVATMTI NFWNKTINPD IFVMVFLLFV
IFINLCGAKG YAYSEMIMNS TKIFMLTGFC IFGLVMVLGG GPEGWVGGRY YHDPGAFTSF
KGIAGVFVTG AFSLGGSEFI SLSAAETKHP RRSLRAASKL VYVKVIVLFL GSLTFIGLLV
PYNHPRLTGS GSSSSTSPYV LATLIHGVPH LSHVINSVIL ISVTSVSIAA MYSSQRLVQS
LAHQGLGPKW LDYVDRKGRP ARAFLVCIIA SFFSFIAAYD QQEAVFTWLL SISALSFIFV
WMFICVCHIR FRAALKYRGI KVSSLAYVSP TGLWGSYLSI AINIFMLGCQ FWVALWPIGG
DGKPDVMSFF QNYLAVPCFI VFYLGHKIYT GNWKLFKRVD EIDIDTDRVI YDREILDLEN
TEDKEKYDQA PFWKKILIKC FD
//
