ID G3AJE9_SPAPN Unreviewed; 455 AA.
AC G3AJE9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN ORFNames=SPAPADRAFT_60044 {ECO:0000313|EMBL:EGW34608.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW34608.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|RuleBase:RU004453}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL996500; EGW34608.1; -; Genomic_DNA.
DR RefSeq; XP_007374192.1; XM_007374130.1.
DR AlphaFoldDB; G3AJE9; -.
DR STRING; 619300.G3AJE9; -.
DR GeneID; 18873193; -.
DR KEGG; spaa:SPAPADRAFT_60044; -.
DR eggNOG; KOG4701; Eukaryota.
DR HOGENOM; CLU_007818_7_2_1; -.
DR InParanoid; G3AJE9; -.
DR OMA; IAGRRTH; -.
DR OrthoDB; 360175at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02877; GH18_hevamine_XipI_class_III; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR045321; Cts1-like.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR45708; ENDOCHITINASE; 1.
DR PANTHER; PTHR45708:SF49; ENDOCHITINASE; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..455
FT /note="chitinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003442439"
FT DOMAIN 24..302
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 321..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 455 AA; 47735 MW; 7D2DE930AA2F015E CRC64;
MLTRIISILT ILSTVIAFNA NSNSNVAAYW GQNAGGSQSS LGSYCSSSAA DIIILSFMNG
FPNLELNFAN QCSDTYGDGL LHCSQIGSDI KSCQSQGKIV LLSLGGATGN YGFSSDSDAQ
SFATTLWNKF GGGSDSERPF DDAVIDGFDF DMENKLQTGY AAMAAKLRQY FNSDSSKSYY
LSAAPQCPYP DESVGDILSQ VDIDFAFIQF YNNYCSLGGS FNWDTWSSYA KSTSPNKNIK
LYLGLPGSTA SAGSGYADLS TVQQAVSSIK GDPSFGGISI WDISSGENDG FLSGCKNALG
SSSGGSAPSY SAPAFSAPST VVPASSASPS AEFGYPAPAP SSEAPASQEP STSSFQWIPA
DAPATTESDE GTTTVTTLQT LYSTSDTPRH QHVVHKVYVT LTTTVLVPPP TNTPQLGDSP
IQKRDEVATV SQGGATHLTT RLGLVLFSLI SVLFI
//
