ID G3AJU9_SPAPN Unreviewed; 717 AA.
AC G3AJU9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 13-SEP-2023, entry version 59.
DE RecName: Full=U3 small nucleolar RNA-associated protein 25 {ECO:0000256|ARBA:ARBA00015422, ECO:0000256|RuleBase:RU365070};
DE Short=U3 snoRNA-associated protein 25 {ECO:0000256|RuleBase:RU365070};
GN ORFNames=SPAPADRAFT_134197 {ECO:0000313|EMBL:EGW34000.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW34000.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC processing, specifically at sites A0, A1, and A2.
CC {ECO:0000256|ARBA:ARBA00002883, ECO:0000256|RuleBase:RU365070}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC composed of at least 40 protein subunits and snoRNA U3.
CC {ECO:0000256|RuleBase:RU365070}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU365070}.
CC -!- SIMILARITY: Belongs to the UTP25 family.
CC {ECO:0000256|ARBA:ARBA00009223, ECO:0000256|RuleBase:RU365070}.
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DR EMBL; GL996500; EGW34000.1; -; Genomic_DNA.
DR RefSeq; XP_007373584.1; XM_007373522.1.
DR AlphaFoldDB; G3AJU9; -.
DR STRING; 619300.G3AJU9; -.
DR GeneID; 18869789; -.
DR KEGG; spaa:SPAPADRAFT_134197; -.
DR eggNOG; KOG2340; Eukaryota.
DR HOGENOM; CLU_018705_0_1_1; -.
DR InParanoid; G3AJU9; -.
DR OMA; FHFYHQY; -.
DR OrthoDB; 5473087at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010678; UTP25.
DR PANTHER; PTHR12933; ORF PROTEIN-RELATED; 1.
DR PANTHER; PTHR12933:SF0; U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG; 1.
DR Pfam; PF06862; UTP25; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365070};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU365070};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365070};
KW rRNA processing {ECO:0000256|RuleBase:RU365070}.
FT REGION 1..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..69
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..100
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..129
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 717 AA; 84005 MW; C485BE0084C6A8DA CRC64;
MARQVKRKSH NRGDHVVDLT KRTKHGRAQM RTVTRTAARK PRDHQEPEQE EIESSEEEPE
VEEEQEEEFD KGQVYNALLT LLKSDHKEHK PKKRVAEQST EEQVEEEEEE EDNVAGINME
EEEEDADEDV DDHIDFVDED EESPKGLNQD PYEVHFNQPL DDYMASQEKL CVKENQKWNI
TDKKVLNDLS LTSMLQVPPG ESVSRPLSNV NSLDDYLIKK KVLDAYKREY SEDLTDLEST
LLEPILNYVD VSYQYKHFKN TQYRKLYILH ALNHIYKTRD RILKNTTKLH SYRESLKSKE
GEVEDEEPEY RDQGFTRPKV LILLPTREAC YEVVETMIQL SGTEQQENKK KFTTQFHTPA
EPPNNKPDDF IDAFKGNNND FFCIGMKFTR KSLKLYSSFY SSDIILASPI GLSMILENPD
KKKRQYDFIS SIEVLIIDRA NQIEMQSWDH VNTVMKYVNK IPKEFHDADF SRIRMWSIND
QAKLLRQTLV FSEFQTPMIN NLISHKSFNL AGKLKFKPII TQENSIMNSI GLKIKQIFQR
FESPSPMSDP DSRFKFFTNT ILPSLLKSSS YEDGIMIFIP SYFDYLRVKS HLKANTKFNF
ASIDEYTSQS KLTRTRQQFT SGKIKILLYT ERLHYFRRFE ISGVKTLVMF GLPSNPVFYK
ELIRFIGKSV FKQECDLDLA LVKILFSKWD AVTLERIVGN ERAPVLCNSV NESYEFR
//
