ID G3AVA9_SPAPN Unreviewed; 713 AA.
AC G3AVA9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 03-MAY-2023, entry version 41.
DE RecName: Full=Nucleolar complex-associated protein 3 {ECO:0000256|PIRNR:PIRNR028977};
GN ORFNames=SPAPADRAFT_143913 {ECO:0000313|EMBL:EGW29912.1};
OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Spathaspora.
OX NCBI_TaxID=619300 {ECO:0000313|Proteomes:UP000000709};
RN [1] {ECO:0000313|EMBL:EGW29912.1, ECO:0000313|Proteomes:UP000000709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-27907 / 11-Y1 {ECO:0000313|Proteomes:UP000000709};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- FUNCTION: Required for synthesis of 60S ribosomal subunits and the
CC transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
CC {ECO:0000256|PIRNR:PIRNR028977}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|PIRNR:PIRNR028977}.
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family.
CC {ECO:0000256|ARBA:ARBA00007797, ECO:0000256|PIRNR:PIRNR028977}.
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DR EMBL; GL996506; EGW29912.1; -; Genomic_DNA.
DR RefSeq; XP_007377678.1; XM_007377616.1.
DR AlphaFoldDB; G3AVA9; -.
DR STRING; 619300.G3AVA9; -.
DR GeneID; 18870585; -.
DR KEGG; spaa:SPAPADRAFT_143913; -.
DR eggNOG; KOG2153; Eukaryota.
DR HOGENOM; CLU_012441_3_1_1; -.
DR InParanoid; G3AVA9; -.
DR OMA; HYCPQVR; -.
DR OrthoDB; 24935at2759; -.
DR Proteomes; UP000000709; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR011501; Noc3_N.
DR InterPro; IPR016903; Nucleolar_cplx-assoc_3.
DR PANTHER; PTHR14428; NUCLEOLAR COMPLEX PROTEIN 3; 1.
DR PANTHER; PTHR14428:SF5; NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG; 1.
DR Pfam; PF03914; CBF; 1.
DR Pfam; PF07540; NOC3p; 1.
DR PIRSF; PIRSF028977; Nucleolar_complex_p3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000709};
KW Ribosome biogenesis {ECO:0000256|PIRNR:PIRNR028977}.
FT DOMAIN 131..221
FT /note="Nucleolar complex-associated protein 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07540"
FT DOMAIN 509..698
FT /note="CCAAT-binding factor"
FT /evidence="ECO:0000259|Pfam:PF03914"
FT REGION 1..126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..119
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 713 AA; 81641 MW; 40D042D94006E1E6 CRC64;
MGKRKQNAEK LAKRKKLKQE QDAQLSTGLF ASTTQVSDEE GNDWDNEEQE YELKPRNVKN
VKTVESLPIK KSDGTIERVV REVEIEEEEP ASEEEEPEVE EEKPQEDEKE EEEEEEDEDA
HLTPQQKLIK IKEEIADLAS KLIENPEENI SCLTRLRKMS ESKNFVTSQL AIMALIPIFK
SLAPSYKIRP LSDVEKREKV SREVAKLRTF EQSLVTNYIA YIDTLTQFSK VSYSNSANNK
KITSDHLKRG FLATTAATEL CLSSLRHFNY RSELFSIVIK RLNRKPTNPQ DYQVFMKCLR
VLETLLKDDA ENGDITFDVI RIMTKTIRDK KFRVDESVIN VFLSLALLED YDPNNNRDDL
PKPKLKKKDR VHLSKKERKA RKERKEIEEE MRKAEQAITV EEREKYQAQV LKMILTLYLE
ILKAGSHSVD AGEKDAALLM GAVLEGLSRF GQMANFDLLG DFLEVLREIM NDIVEEHSMG
HFNSIVDGKI DETDDQGGMY SGKQIRTVLL CIATSFSLVL NHQSTGRLPM TIDLSKFVST
LYLVLADLAL DPDLEFSHKT LRLADPLSIA NEVEKPAINV STKAELLLRC LDFIFFRSKN
GTTPRATSFT KRLYLSFLQT PEKTSLAGLK FIGKLMNRYD EAVKGLWNTE ERISGEGTYN
LGIEREDREV ELERSNSEAA TLWENVLLDK HYCPLVRDGS RSLMKNSKAG AQR
//
