ID G3B182_CANTC Unreviewed; 1150 AA.
AC G3B182;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=CANTEDRAFT_104194 {ECO:0000313|EMBL:EGV64902.1};
OS Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC
OS 10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Yamadazyma.
OX NCBI_TaxID=590646 {ECO:0000313|Proteomes:UP000000707};
RN [1] {ECO:0000313|EMBL:EGV64902.1, ECO:0000313|Proteomes:UP000000707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 /
RC NRRL Y-1498 / VKM Y-70 {ECO:0000313|Proteomes:UP000000707};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR EMBL; GL996515; EGV64902.1; -; Genomic_DNA.
DR RefSeq; XP_006685708.1; XM_006685645.1.
DR AlphaFoldDB; G3B182; -.
DR STRING; 590646.G3B182; -.
DR GeneID; 18245695; -.
DR KEGG; cten:CANTEDRAFT_104194; -.
DR eggNOG; KOG0414; Eukaryota.
DR HOGENOM; CLU_001867_1_0_1; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000000707; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR Pfam; PF20168; PDS5; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000707}.
FT DOMAIN 67..222
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 965..1125
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 455..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..491
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1150 AA; 129759 MW; 4754BE0AD6C323CF CRC64;
MADFNLTAYF NSFDVEKLSD DRLPDSSNRL ESLIENLANN PESLSYNNDL FEDAVELTHG
LNGLQLNQRK QLSYLMASSF KSVSSNINLA IQSGDFVESL PNFKTLLEKY GYFLFVLFTI
LGKEDFSGIS VSKAKSKNAD QQAWQANQTQ VQDLLDAAES CLSIDLSKVF VTTPEKSAFI
ELFNRPIFHL METPERMKVA ATTTLMFRCI CMMVKSHNHG STVQNSIIQS LTYFIHLPPY
MGELLHKLDS EYDYGALTED VLREVSQIEF NSNDSNGPKA VSEFLVSLSQ LSPRLILKQM
PSIAQLLDNS NQTLRCSVVE SCGNIVVDII KSTETSQSST EQESAHRNEN GTHQTESLID
LLQERLLDQN PYVRTKAIQA LNKICSLPVK FTRRRQIIMA LTVRSLEDRS TLVRRNAVKL
MSKLVLNHPF ASIHGTQLSL SKWQKRCDEA NEALKQYLPL IPEPEKDNED REEPDNNSKD
DDMEIDNNED SDSQDSDARE QLNTSMREQE GNLPNAEILV KTKLTAQYYE DAVDFITVVH
KGTELVSNLL FSKNRNEVLE SMDFLVLADA FGIDNASYGI KRMLHLVWMK GSSDEGKSIA
SHLIDCYKEL FLTVPDNISS TQKGSLVAKN LIGITLTSTL ADLASFEKLL CNMYFEKLIS
DEVISILWQI YGHKTDDLSE EHLESSHSQR RGAIIVLGML ALADYQVVLR GLDLLLNIGL
NVEGYEDSEL YKYSCIALQR IVPTLSKSKD TTFYKVEREE EIIEKLGNVL TTEYEDPSWY
SVAEQAISSI FRISNSPDTV CTEIINRRSV SLFANGNPST QVHSLAQLLF IVGHVAIKTI
VYLEKLETFF KKKKQDKEVK GSKADNDDDN EENELEMIGG TTEDDFADAV IYIKEKEILY
GETSLLARFA PIVKEICSNN KSYDSTILQR SASLCMVKLM CISSKFCEES LPLLITIMER
SPDPIVRSNC VLGLGDMAVC FNNLVDENTD FLYRRLTDEN IMVQRTCLMT VTFLILAGQV
KVKGQLSSMA KCLENEDQGI SDMCRLFFTE LATKDNAIYN GFIDIFSGLS NDATLEKESM
KRIVKFLVSF IEKEKHQKQL SEKLLVRLNK TQSADQWNDV AFVLSSIPYK NESITKALED
GFKLVEAGGR
//
