ID G3B643_CANTC Unreviewed; 635 AA.
AC G3B643;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=RhoGAP-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CANTEDRAFT_135199 {ECO:0000313|EMBL:EGV63375.1};
OS Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC
OS 10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Yamadazyma.
OX NCBI_TaxID=590646 {ECO:0000313|Proteomes:UP000000707};
RN [1] {ECO:0000313|EMBL:EGV63375.1, ECO:0000313|Proteomes:UP000000707}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 /
RC NRRL Y-1498 / VKM Y-70 {ECO:0000313|Proteomes:UP000000707};
RX PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA Barry K.W., Grigoriev I.V., Gasch A.P.;
RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT production.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
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DR EMBL; GL996524; EGV63375.1; -; Genomic_DNA.
DR RefSeq; XP_006687168.1; XM_006687105.1.
DR AlphaFoldDB; G3B643; -.
DR STRING; 590646.G3B643; -.
DR GeneID; 18249856; -.
DR KEGG; cten:CANTEDRAFT_135199; -.
DR eggNOG; KOG1450; Eukaryota.
DR HOGENOM; CLU_010730_2_0_1; -.
DR OrthoDB; 5482027at2759; -.
DR Proteomes; UP000000707; Unassembled WGS sequence.
DR GO; GO:0005933; C:cellular bud; IEA:UniProt.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07652; F-BAR_Rgd1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF136; RHO GTPASE-ACTIVATING PROTEIN RGD1; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000707}.
FT DOMAIN 13..278
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 436..631
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 309..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 169..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 317..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 71030 MW; 297630FCE1AC6A31 CRC64;
MSEIEAPRLL ESDQIINILN NDGSLDLLLN RLKKSVTTGE EFSKYIKKKA IIEDDHYSQL
KKFGSQSRQA LKNPSKLKED SFSDKLDKII EFDEKLYGVG SSYVTALNVM YDELTSLIAA
VIRSRKQIKE EGKRKEKDCQ DSIQAAEKAK MKYNHLCDDL DKLKNGDPKK TFSLKNKSYE
QQEDDLQRKV DLADQDYRSK VATCKKLKDE ILMVYRPTHT KKLKNLVLEM DIAMNVQLQK
LATWNETLIM NSGVLVAPLT SSKPSMKELA NAVDNEKDLY NYILRSEKEF AQNRSSLVPI
EYKVHPSLAK YEPPKSNKPF LNNSNPKNVS NMALPPVSTA LYESTSSSGS NTNYANNSVN
DSGLSTSGSG NVNNSYGAPR SPSGVSDAQT ALTYNSLDPN SQPNTPELNG VKSLSQVSHA
NLGSSTSSNS QPTFGVSIEE LINFAGIDNV PLVVKKCIEV IETHGLELEG IYRKSGNVSI
VQNLRESIDK KFTNYLLIGN NIDPTNVIDT DIYCIASLLK LYFASLPEPL LTEEFYQSFI
ETVKSLDENF IAKKLHHLVY NLPDGAYFTL RALIFHLNTV ASKSDTNRMT VKNLAIIWGP
AILNDNSMNP QDLSYKSKVV EELMLIANDI FDTED
//
