ID   G3B6Q9_CANTC            Unreviewed;       875 AA.
AC   G3B6Q9;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=Gdp-GTP exchange protein for the Rho1p small GTP-binding protein {ECO:0000313|EMBL:EGV62993.1};
GN   ORFNames=CANTEDRAFT_122634 {ECO:0000313|EMBL:EGV62993.1};
OS   Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC
OS   10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Yamadazyma.
OX   NCBI_TaxID=590646 {ECO:0000313|Proteomes:UP000000707};
RN   [1] {ECO:0000313|EMBL:EGV62993.1, ECO:0000313|Proteomes:UP000000707}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 /
RC   NRRL Y-1498 / VKM Y-70 {ECO:0000313|Proteomes:UP000000707};
RX   PubMed=21788494; DOI=10.1073/pnas.1103039108;
RA   Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., LaButti K.M.,
RA   Sun H., Clum A., Pangilinan J.L., Lindquist E.A., Lucas S., Lapidus A.,
RA   Jin M., Gunawan C., Balan V., Dale B.E., Jeffries T.W., Zinkel R.,
RA   Barry K.W., Grigoriev I.V., Gasch A.P.;
RT   "Comparative genomics of xylose-fermenting fungi for enhanced biofuel
RT   production.";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011).
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DR   EMBL; GL996524; EGV62993.1; -; Genomic_DNA.
DR   RefSeq; XP_006686786.1; XM_006686723.1.
DR   AlphaFoldDB; G3B6Q9; -.
DR   STRING; 590646.G3B6Q9; -.
DR   GeneID; 18248914; -.
DR   KEGG; cten:CANTEDRAFT_122634; -.
DR   eggNOG; KOG4305; Eukaryota.
DR   HOGENOM; CLU_001251_2_1_1; -.
DR   OrthoDB; 5100844at2759; -.
DR   Proteomes; UP000000707; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd04435; DEP_fRom2; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR041675; PH_5.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR46572:SF2; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF00610; DEP; 1.
DR   Pfam; PF15405; PH_5; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00036; CNH; 1.
DR   SMART; SM00049; DEP; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   PROSITE; PS50219; CNH; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000707}.
FT   DOMAIN          187..377
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          559..850
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
SQ   SEQUENCE   875 AA;  101100 MW;  FB3C47FC65CFF244 CRC64;
     MSKKPSVYPA MLSRVARVFR ESIFLTINTK DGLEYHDTFT GKMAVDIICR IIRTNDRNLA
     LLLGRSLDSQ KFFHDVTYQH RLRDSIHEVY AFNHIYSDSP ISGTGVNGVF TILTDCYSPT
     CSRNSLCYSI ACPRRLEQQA RLNMKPQGGL QRAVSRLSLH DQDETKSLWH ETVPKSVLDK
     LDKLEKMRQE LIYEFIYTER DYVKDLEFMT DFYIMPLRNP SNNIIPERER EVFIRTVFGG
     VSDLLRLAKS ISEALTRRQQ QQKPVIQTIA DVFLQFVDKF EPFIQYSGNK VFASFEHERQ
     QQVNMRYASF LDAIEKRPES RKQDLSSFLI KGIQRPARYQ LLLGGILKNT QPDSPDYPDL
     LKAKEEIEKI LGKINIQTGE STDRHKIMVL HRLLGKQTLE DKYNFKLSYN NRIIYQVTLN
     RKRDNEKIDL YLFEHALLLV KHKIQNKREQ YKVFEKPIYL PLLFVNSGYD IPTFRTVINS
     RINGSIMSES KAKVDSINTK LQINFMGLGS QQVHTTLNAD DVANQNQVLS QISSQQKKIM
     AKYDIFSLSK YETRRFTGNN KINCAVPCYG GKKLLYGTDS GVWVSTVRTI SITNNEKICS
     DPTLVISKEY VTQIEVLVEY SKLLVLSDKS LFEFDLSCTD SLDHAKNTRS GRLILSHVSS
     FKTGICDGKL LVCCIKQGNN HSINIFEPPN PFDKNKNRNK KYDIREITFS SDPISISFLR
     TRLCIGCTKG FEILSMEDGK KEPILDEADP SLDFATQKEI VNPLAIHRLG KDFLLSYSEF
     SFLINRNGWR TKHDWGIFWE GNPTNIALFY PYLLSFESNF IEIRDLKTTY LIRALIGENI
     RFLHSNEHEA MYACEEGGYD VIVSIDFLNL KPKEK
//