GenomeNet

Database: UniProt
Entry: G3GRF9_CRIGR
LinkDB: G3GRF9_CRIGR
Original site: G3GRF9_CRIGR 
ID   G3GRF9_CRIGR            Unreviewed;      2981 AA.
AC   G3GRF9;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   10-FEB-2021, entry version 41.
DE   SubName: Full=Centromere protein F {ECO:0000313|EMBL:EGV92559.1};
GN   ORFNames=I79_000105 {ECO:0000313|EMBL:EGV92559.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC   Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV92559.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA   Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA   Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA   Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH000002; EGV92559.1; -; Genomic_DNA.
DR   RefSeq; XP_007641800.1; XM_007643610.2.
DR   STRING; 10029.XP_007641800.1; -.
DR   GeneID; 100752075; -.
DR   KEGG; cge:100752075; -.
DR   CTD; 1063; -.
DR   eggNOG; ENOG502QVMD; Eukaryota.
DR   InParanoid; G3GRF9; -.
DR   OMA; YNAQLVQ; -.
DR   OrthoDB; 205405at2759; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0005930; C:axoneme; IEA:Ensembl.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR   GO; GO:0097539; C:ciliary transition fiber; IEA:Ensembl.
DR   GO; GO:0000940; C:condensed chromosome outer kinetochore; IEA:Ensembl.
DR   GO; GO:0030496; C:midbody; IEA:Ensembl.
DR   GO; GO:0005635; C:nuclear envelope; IEA:Ensembl.
DR   GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0045120; C:pronucleus; IEA:Ensembl.
DR   GO; GO:0000922; C:spindle pole; IEA:Ensembl.
DR   GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0008022; F:protein C-terminus binding; IEA:Ensembl.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR   GO; GO:0008134; F:transcription factor binding; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0051310; P:metaphase plate congression; IEA:Ensembl.
DR   GO; GO:0000278; P:mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl.
DR   GO; GO:0015031; P:protein transport; IEA:Ensembl.
DR   GO; GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IEA:Ensembl.
DR   GO; GO:0016202; P:regulation of striated muscle tissue development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 3.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT   DOMAIN          1..306
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1875..2017
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2113..2252
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2296..2434
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2836..2880
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          208..235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          252..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..492
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1123..1143
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1647..1678
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2760..2843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2857..2981
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          164..191
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          279..412
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          522..684
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          717..758
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          823..878
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          897..931
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1002..1022
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1027..1082
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1205..1239
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1392..1412
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1534..1629
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1802..1829
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1949..1979
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1998..2053
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2089..2109
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2117..2151
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2159..2214
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2306..2442
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2450..2477
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2485..2519
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2544..2585
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2611..2631
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2636..2694
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2704..2731
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2739..2759
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        474..492
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2760..2828
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2829..2843
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2891..2959
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2981 AA;  341165 MW;  8E65D3214D335CB0 CRC64;
     MSWALEEWKE GLPTRALQKI QELEGQLDKL KKEKQQRQFQ LDSLEAALQK QKQKVEDGKT
     EGADLKRENQ RLMEICENLE KAKQKVSHEL QVKESKVNFQ EGQLSSCKKQ IEKLEQELKR
     CKSELERSHQ AIQSMDVSLN PCSTPQKLFT TPLTPSQCYI GSTYEDLKEK YNKEVEERKK
     LEAEIKALHA KNVSQPVPQA TMNHRDIARH QASSSVFSWQ QEKTPSHLSS SSLKTPLRRD
     VSASHFWGEE VTPNRSSLQT GKRDCSSSFC DDPSSSQLLE QVKAQNQDLK SKMNELELRL
     QGQEKEMKGQ VNKFQELQLL LEKTKMELTE KEKVLNKTRD ELVRTSAQCD QAAAKCITLE
     QKLKNLTEEL SCQRQNAESA RCSLEQKIKE KEKELQEELS RQHRSFQALD QEYTQMKTRL
     TQELQQAKHA LNVLQVEQEK VVSVKQQLER SLEEFRQKLN KTEQALQESQ ITENELRRST
     EEMKKENSLI RNQSEQRARE VCHLEDELGK VKVCLSQSQN FAEDMRAKNT SQEIMLRELQ
     EKLNQQENSL ILEKLKLALA DLEGQRDCSQ DLLKKREHHI EQLNDKLNKI EKEFEALLSA
     LELKKKECEE LEEEKTQFSC WKSENEKLIN QIESEKESLQ SKINHLEASL RTQQIQSHDY
     SERVRTLEME RENLNVEIRN LHSMIDSKMV EIETQKQAYL ELQQKAEFSD QKHQKEIENM
     CLKANELTGQ VEDLEYKLQL LSSEVVTKEQ QYQGLRTEYE TLRDLLKSRG SLVTNEDNQR
     SSLAFEQQPT VSDSFGNLMG EQGSMYSERS DCFVDGDQTS ENLSVLQNRV TSLESSLESQ
     NQMNSDLQKQ CEELLQIKEE IEENLIKAEQ IHQNFVDETN QRIGKLQEDS AVHQNIVAET
     LATLESKEKE LQLLKEKLEA DQTEIQELKK SNCLLEETLK ELQLSSETLS SEKKEMSDII
     SLNKKDIEEL TQENGALKEV NEALWQEKMN LLQKHEEISR CVAEQERSIS ELSDQYKQER
     HLLLQRCEET ETVLEDLRGN YKTAQENNAR LECLLSECTA ACENRKNELE QLKEAFAKEQ
     QEFLTKLAFS EEQNRKLMLK LEIEQQTVKS KITDTKIYSK SETDGLRQET LKEEQNKKEK
     EVSNLHENEQ LMQLTQTKHE HYHLEVESVE NSVKATEDEI NMCSSQCQMD IDTKDISPDS
     YKAQLVQLEA LIKVMEVKLD QSEEEKKTLH QELQTIRGEL ETVSSQDTQS HERIGLKDCE
     IEAEGKYVSV LHELSTSQNE NAHLQCSLQT ALNELTELGK VCEVLKVEKL KLQSELNDSR
     SQCITATSKM AAEVEKLVNE VKILNHEGVL PQSKLMKDVS DVLHDKRNMT PLDSSGFCEQ
     ITLSDKEVPV HFAELQEKFS CLQNEHKILH DQHCEVSSKM SELCSYVDTL QAENSVLSVN
     LRNLKGDLVK ERKPGAENGH TLSVSFCGTD SPSLTNFGEA LYKDVLEQTD NTSLLSLEGN
     ASANPCNVDD VSYSSLEEEN LTEKEIPAAS VRTIEELEIL CQVYLQSLKN LEEKIESQGI
     MKNKEIQELE QLLSSERNEL GCLREQYLSE KEQWQQKLTS VTLEMESKLA EAKQQTKNLS
     LELEVARLQL QELDLSSRSL LGTDMENAVQ GQNDSYDIKE SEVSVSETTE KTSTQDTDQT
     CDKDVQQDLC LETLITKTET ARFTGEGCEE QSLQTNCEAS AEDKTQDYSE CISELFSSPN
     VLIPMDILED QGSSQNLHLQ KDTSNENLRL PPVVDDWDKK VESLLNEIKE SGSKLSLQEV
     QLKIKIETCM QLEKIVKDLK KEKSDLSEKL ESLPCNQEVH QRIESREDLV FDVELGTSKL
     SGAIKDSAAN IEDNWKEKFL DVEKELIRIQ SEKANLEHLI LSVEADLKVV QAEKLHLERD
     TESKQKVIVD LKEELFVVIS ERNRLCGELD TVSEERKALD QMSKKMKEKV EELESHQSES
     LRHIEVVEAE VKDKAELLQT LSFNVSELTK DKAHLQEQLQ SLQNDSQGLS LAVGELEIQI
     GQLSKEKESL VKESQNFQVK LTETECEKQN ISKALEVALM EKGEFAVRLS STQEEVHQLR
     RGIEKLSVRI KADEKKHFST EEKLKESQRE NDSLKDKVEN LERELEMSEE HQELVILDAE
     NSKAEVETLK AQMDEMAKNL SVFELDLVTV RSERENLTRQ LQDKQSRVSE LDELCSSFRS
     LLEEKEKARV QMEEDSNSAV LMLQTQLQEF SEQIAALCND QETSKTQEQS LDQAGEEVHP
     LKSSIQKLKA RIHAGEKEQH CLLGQLRESK HYADVLKDRV ENLEQELKLS EANREHVTLK
     AESSKAEIQT LKSEIQGMVQ NIQDLELELT NTRSENENLM KGLKQEQKRV SELETKNSSI
     ENLLKEKEQE KVQMEEESKI TMERLQTQLR ELNETMISLC NDQEAYKTKE QNLSGQVQTL
     EVEKAQLLQD FGETKNKYIS LQSSVNVLTQ EIKDGKQKLE KKEEEVRTLE DQLKGQEQLV
     CKLSQLEGEQ QLWQKQKVEL GNLTVELEQK IQVLQSKNSA LQHTFEALQN SYKSLESELG
     LMKTEKVSLV QRINTMIGKE AQLQRELHLM VQKTTRLKEE FNKEKNRLTE ELKVPVEELK
     NLKVEHCKSV NQLEKEFQRA QGKIKLLLKS CKQLEREKGM LEKEICQLEA AQKQKAGTVV
     GDNVAKLMTE NKELKETLEE KIKEADKYLD KYCSLLISHE ELEKAKEMLE LQVARLSSQQ
     SKQHLHSSSL LNSSVPGPSP ATSVSEKSTS GQSKTSGKRQ RSSGIWENGS GTPPCAPETF
     SKKSKKTVNS SVHPTEDKEE TKFELEGLPE VVKKGFADIP TGKTSPYILR RTTMPIRTSP
     RLAAQKLVGS SPTPGKENIA ESSKPTAGGS RSQKVKVVQQ SSVDSCTAIP ESLEKSLTAC
     NVPGRNSAES PTEDLSIKQG YPASSPAAGP NPPINENCRV Q
//
DBGET integrated database retrieval system