ID G3GSV4_CRIGR Unreviewed; 854 AA.
AC G3GSV4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=Protocadherin-10 {ECO:0000313|EMBL:EGV99688.1};
GN ORFNames=I79_000726 {ECO:0000313|EMBL:EGV99688.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV99688.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000014; EGV99688.1; -; Genomic_DNA.
DR AlphaFoldDB; G3GSV4; -.
DR STRING; 10029.G3GSV4; -.
DR InParanoid; G3GSV4; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 5.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF0; PROTOCADHERIN-10; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..854
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003443682"
FT TRANSMEM 672..696
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..122
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 123..211
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 209..316
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 317..421
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 422..532
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 548..638
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 643..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 854 AA; 93141 MW; 153DDF908E835E63 CRC64;
MIVLLFFALL WMVDGVFSQL HYTVQEEQEH GTFVGNIAED LGLDITKLSA RRFQTVANSR
TPYLDLNLET GVLYVNEKID REQICKQSPS CVLHLEVFLE NPLELFRVEI EVLDINDNPP
SFPEPDLTVE ISESATPGTR FPLESAFDPD VGTNSLRDYE ITPNSYFSLD VQTQGDGNRF
TELVLEKPLD REQQAVHRYV LTAVDGGGGQ PVYTVSLPEN SPPGTLVIQL NATDPDEGQN
GEVVYSFSSH ISPRARELFG LSPRTGRLEV SGELDYEESP VYQVYVQAKD LGPNAVPAHC
KVLVRVLDAN DNAPEISFST VKEAVSEGAA PGTVVALFSV TDRDSEENGQ VQCELLGDVP
FRLKSSFKNY YTIVTEAPLD REAGDSYTLT VVARDRGEPA LSTSKSIQVQ VSDVNDNAPR
FSQPVYDVYV TENNVPGAYI YAVSATDRDE GANAKLTYSI LECQIQGMSV FTYVSINSDN
GYLYALRSFD YEQIKDFSFQ VEARDAGSPQ ALAGNATVNI LIVDQNDNAP AIVAPLPGRN
GTPAREVLPR SAEPGYLLTR VAAVDADDGE NARLTYSIVR GNEMNLFRLD WRTGELRTAR
RVPAKRDPQR PYELVIEVRD HGEPPLSSTA TLVVQLVDGA VEPQGGGGGG GGGPGEHQRP
SRSGGGETSL DLTLILIIAL GSVSFIFLLA MIVLAVRCQK EKKLNIYTCL ASDCCLCCCC
CGSGGSTCCG RQARARKKKL SKSDIMLVQS ANVPSNPAQV PVEETGSFGS HHHNQNYCYQ
VCLTPESAKT DLMFLKPCSP SRSTDAEHNP CGAIVTGYSD QQPDIISNGS ILSNEVRLKR
KNHHLSSPPS ESLL
//
