ID G3GUI0_CRIGR Unreviewed; 870 AA.
AC G3GUI0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Ovostatin-like {ECO:0000313|EMBL:EGV98478.1};
GN ORFNames=I79_001342 {ECO:0000313|EMBL:EGV98478.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV98478.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000031; EGV98478.1; -; Genomic_DNA.
DR AlphaFoldDB; G3GUI0; -.
DR STRING; 10029.G3GUI0; -.
DR PaxDb; 10029-XP_007627245-1; -.
DR eggNOG; KOG1366; Eukaryota.
DR InParanoid; G3GUI0; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.60.40.1930; -; 2.
DR Gene3D; 2.60.40.1940; -; 1.
DR Gene3D; 6.20.50.160; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR InterPro; IPR041555; MG3.
DR InterPro; IPR040839; MG4.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR PANTHER; PTHR11412:SF174; OVOSTATIN HOMOLOG 1-RELATED; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF01835; MG2; 1.
DR Pfam; PF17791; MG3; 1.
DR Pfam; PF17789; MG4; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 4: Predicted;
KW Bait region {ECO:0000256|ARBA:ARBA00023248};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..870
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003443884"
FT DOMAIN 455..601
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
FT DOMAIN 738..828
FT /note="Alpha-2-macroglobulin"
FT /evidence="ECO:0000259|SMART:SM01360"
SQ SEQUENCE 870 AA; 97578 MW; 3B03CDF0A4762AA7 CRC64;
MLLLKIPGGR WDKMVPTVLL SALLLHLTDA VASEPRYILW VSSVVQRFSP EKACLHLSNL
SESVSLSVIL EYDGSNTTIF DQSVEAGDFY ACNNFKVSQT SSEPLAFVTL LAQGNTLKIS
ERRAVAIAAE ENTTFVQTDS PIYKPGDTVN FRIVTLNTWL KPVDDLDPEH NVIFQWKNVT
TLRNITQLSF HLTPEPMFGD YTIVIRKQSG MTVVHLFSVN RDVLPKFEVE VSAPETITIA
DNQFQVVACA KYTYGQSVQG KVQIRVCREF SSSGYCESNS NNEICEQFTE QLKDGCISQA
VNTKVFQLYR SGLFMTFNVN VMVTEFGTGV QISKTHPVFI TSVLGSVIFE NMDSFYRRGI
TYSGTLRFSG SNNAPMVRKL LQLELNGKFL GNYTTDENGE AQFSIDTSEI FDAQISLKAI
YVRPRICHRP SWLDPEYLDA YFSVSRFYSR TNSFLKIVPE PEQLPCNQEK MVSVLYSLNP
EAYKDASGVN FFYLVMARGS IFLSGQKEVR SQAWNGSFSF PIRISADLAP LAALFVYTLH
PSGEIVADSV KLQIDKCFKN KVSIKFSKEQ DLPGSTTRLH LQAAPNSFCG LRAVDKSVLL
LKPEQELSPE SVYNLLPNIH PYGYFYHGLN LDDDRVNPCI PQKDLFHNGL YYTPASNSWD
GDIANLLRDM GLKVFTNFHY RKPEICSSQE NLHLLRTFDG PQGPMMYGAP AAFRDAVDSI
NHAEQAIRET VRTHFPKTWI WDLISVDSSG SANVSFLVPD TITQWEASAF CVNGEAGFGI
SPKAYLQISQ PFFIEIASPF SIVRNEQSDV VVSVFSYLTT CVELEASENY EANINTLSNN
GSDVLQAGER KTYVWTIIPK TLGKQLSFLD
//
