ID G3GXS4_CRIGR Unreviewed; 277 AA.
AC G3GXS4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Cell growth regulator with EF hand domain protein 1 {ECO:0000313|EMBL:EGV95863.1};
GN ORFNames=I79_002567 {ECO:0000313|EMBL:EGV95863.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV95863.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000061; EGV95863.1; -; Genomic_DNA.
DR AlphaFoldDB; G3GXS4; -.
DR STRING; 10029.G3GXS4; -.
DR PaxDb; 10029-XP_007613670-1; -.
DR eggNOG; ENOG502S2TZ; Eukaryota.
DR InParanoid; G3GXS4; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23104:SF15; CELL GROWTH REGULATOR WITH EF HAND DOMAIN PROTEIN 1; 1.
DR PANTHER; PTHR23104; MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..277
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005679755"
FT DOMAIN 66..101
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 110..145
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 141..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 30494 MW; 7DCFC35A2523014D CRC64;
MQVLMLPLLL LPLGYTAPKD GAARMDPEVQ QQIMPNPFQP GPEQLQRLRN YLKGLEKMEE
DPEHMNREQV LLYLFALHDY DQNGQLDGLE LLSMLTEALA PGAAHFPINP VILVVDQVLE
TQDLDGDGLM TPAELVNFPG EVPKHAESLP PALQEPQPAG RQLHLANGPL QPEAQQSLET
REETRGQVEA KGESLEPVQK AEHQTGAEVD TLSPEGAVRR QAEAEGDVLS PREDAEGQMG
RKNNEGEPKE LPVGTLDATN TPNEMEAHSI QLENDEI
//
