ID G3GYV7_CRIGR Unreviewed; 2319 AA.
AC G3GYV7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Neurobeachin-like protein 1 {ECO:0000313|EMBL:EGW06134.1};
GN ORFNames=I79_003011 {ECO:0000313|EMBL:EGW06134.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW06134.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000069; EGW06134.1; -; Genomic_DNA.
DR STRING; 10029.G3GYV7; -.
DR eggNOG; KOG1787; Eukaryota.
DR InParanoid; G3GYV7; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF115; NEUROBEACHIN-LIKE PROTEIN 1; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF16057; DUF4800; 1.
DR Pfam; PF20426; NBCH_WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 1617..1909
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2113..2154
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1077..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1077..1092
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2319 AA; 265239 MW; 2A530C1B4C2B2527 CRC64;
MTFSFQKDPD YLRLWLDNFV LSYEQFLDVD FEKLPTRVDD VPPGISLLPD NILQVLRIQL
LHCVQKTADG LEEQQQALSI LLVKFFIILC RNLSNVEEIG TCSYINHVIT MTTLYIQQLK
SKKKEKEMAD QTSIEEFVIH ALAFCESLYD PYRNWRHRIS GRILSSVEKS RQKYKPASLT
VEFVPFFYQC FQESEHLKES LKCCLLHLFG AIVAGGQRNA LQAISPATME VLMRVLSDCD
SWEEGDPEEV GRKRELTLKC LTQVVHILLT SSSDQRQVET STILENYFKL LNSDHSALPK
QRRSRRWESQ FIALQIKMLN TITAMLDCAD RPVLQAIFLN SNCFEHLIRL LQNCKLFLNA
HSMVADKNEK DLANQLLTEI SEDQVFQGRL DCLAVSSIQA LTAVMKNSPA AKEVFKERIG
YMHMFEVLKS LGQPSLELLK ELMNMAVEGD HTSVGILGIS NVHPLLVLIQ WLPELESHDL
QIFISDWLKK ICCINKQSRT TCVNANMGIR IIETLESHSS LHRICAENLI AIHGSLGSQS
VSSEEVRRLL RLLRVDESEL IHPYTIPVTR AILTMARKLS FESALQYFNL SHSMAGISVP
AIQKWPGSAF SFTAWFCLDQ DQLTLGTTNQ RGKRKQLYSF FTGSGMGFEA FITHSGMLVV
AVCTKREYAT VMLPDHSFCD SLWHNITIVH MPGKRPFGQS LVYIYDNGQQ KVSAPLRFPA
MNEVPGTLMD VNVLVAIQLL IEQVSLEKNT QLLQQMYQYL LFDFRIWNRG DFPFRIGHIQ
YLSTIIKDSR RVFRKKYGVQ FLLDTLRIYY GHGCTCNELS PDDIRTIRTS LYGLIKYFLC
KGGTHEEIQS IIGYIAATNE EEQLFGILDI LFSLLRTSPT RGQLFLLMFE PGNADILYAL
LLNQKYSDKL REIIFKVMEQ MLKCTNVYER SKQRIRLREV GYSGMGLLLN EAPVNTSLIK
NLVNQIINAD PVINFKDLLS VVYISHRTHV NVRVALCGKI LQILQSQPDA AYQISQQVGW
QDTFVKLFLK ENFENVNSLH KHGKAVSVKE NKNVSTEKLD DEKMTLADVS SDHWSLEDSQ
SLNSNTPLFQ EDGSEGELSF KSENQEEFWH SNTSHLSLDL SGTDSCELSE SGSQMPDSSP
STPSPVESIK SFSMRSDKER SITNEMDFSD DFLESQEGCE EELLQLLTNI LNYVMSKGLE
KSDEDTWIER GQVFSALTKP GISSELLRPS DEVKLILLQK MLEWAVTENR DAKSSPVTAE
NAFRLMLIIQ DFLQSEGLVN SNVWTEKLLE DTTQLLDCLS VWYSETPVWV KLSQIQLQLL
LEFIGRGSLQ VCAVASAKLN ALLQTKVIEN QDEACFILGK LEHILNRSIK EQTEIYSFLI
PLFRTLVSKI YELLFMNLHL PSLPFTNGSA SFFEDFQEYC NSNEWQVYIE KYIVPYMKQY
EVHTFYDGHE YMALYWKNCY EALMVNMHKR DREGGESKLK FQEYFVEPFN RKARQENLRY
NNMIKQLSNQ QLATFRRWKA IRLYLTCERG PWAERKQNQI HWKLANVENY SRMRLKLVPN
YNFKTHEEAS ALRDNLGVQH LQPSSDSLLL EVVKQVKLSD MEEDKLELLE EDMIARVNID
EKEEQDQKEK LVLTEDCELI TVIDIIPGRL EITTQHIYFH DNSIEKEDDY TSEELDLNNP
TVFRDLSKPI GVVNEKNAKA MQEKYETFED PMGTIDKFHY GTHYSNSAGV MHYLIRVEPF
TTLHIQLQSG RFDCADRQFH SIPATWQALM DNTYDVKELI PEFFYFPEFL ENQNEFNLGY
LQVSKELVND VILPRWAKSP EDFIYKHRKA LESEYVSAHL HEWIDLIFGY KQRGPAAVEA
LNVFYYCSYE GAVDLDALTD EKERKALEGM INNFGQTPCQ LLKEPHPPRL SAEEVIQKQT
KTEISTLNLF QHLPQLKSFF IEGISDGIPL LKAIIPKNQS RSFMSQGSPE LLITISMNYV
IGTHGWLPYD RNISNYFTFI KDQTVTNPKA QRTVNGPFAP GLEITSKLFV VSHDAKLLFS
AGHWDNSIQA MSLTKGKIVS HNIRHIDIVT CLATDYCGIH LISGSRDTTC MIWQITQQGG
TPVGLASKPF QILYGHTDEI LSVGISTELD MAVSGSRDGT VIIHTIQKGQ YMRTLRPPCE
SSLFLTIPNL AISWEGHIVV CSSLEEKPTL KDKNMLHVFS VNGKYLGSQV LNEQISDICI
IGEHVITGSL QGLLSIRELH SLNLSITPLA MRLPIHCVSV TKENSHVLVG LEDGKLIVVG
VGKPAEMRSS QLSRKLWGSS KRLSQISAGE TEYNTQDFK
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