ID G3GYV9_CRIGR Unreviewed; 382 AA.
AC G3GYV9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Abl interactor 2 {ECO:0000313|EMBL:EGW06136.1};
GN ORFNames=I79_003013 {ECO:0000313|EMBL:EGW06136.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW06136.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
CC -!- SIMILARITY: Belongs to the ABI family. {ECO:0000256|ARBA:ARBA00010020}.
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DR EMBL; JH000069; EGW06136.1; -; Genomic_DNA.
DR AlphaFoldDB; G3GYV9; -.
DR STRING; 10029.G3GYV9; -.
DR InParanoid; G3GYV9; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR CDD; cd11972; SH3_Abi2; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR028457; ABI.
DR InterPro; IPR035726; Abi2_SH3.
DR InterPro; IPR012849; Abl-interactor_HHR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR10460:SF26; ABL INTERACTOR 2; 1.
DR PANTHER; PTHR10460; ABL INTERACTOR FAMILY MEMBER; 1.
DR Pfam; PF07815; Abi_HHR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 320..379
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 83..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..159
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..289
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 40845 MW; 4AB1CDFD10664961 CRC64;
MCTHAYVKFC FYHVDYKSQT VDIHKEKVAR REIGILTTNK NTSRTHKIIA PANLERPVRY
IRKPIDYTIL DDIGHGVKVS TQNMKIGGLP RTTPPTQKPP SPPMSGKGTL GSSGSSGGSH
PSSRSSSREN SGSGSVGVPI AVPTPSPPSV FPAPAGSAGT PPLPATSASV PTPLVPATVP
SSTAPDAAAG GAQTLADGFT SPTPPVISSN PPTGHPVQFY SMNRPASRHT PPTIGGSLPY
RRPPSITSQT SLQSQMNGGP FYNQNPVSDT PPPPPPVEEP VFDESPPPPP PPEDYEEEEA
AVVEYSDPYA EEDPPWAPRS YLEKVVAIYD YTKDKEDELS FQEGAIIYVI KKNDDGWYEG
VMNGVTGLFP GNYVESIMHY SE
//
