ID G3H0S5_CRIGR Unreviewed; 424 AA.
AC G3H0S5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE SubName: Full=Tripartite motif-containing protein 69 {ECO:0000313|EMBL:EGV97185.1};
GN ORFNames=I79_003743 {ECO:0000313|EMBL:EGV97185.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV97185.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000098; EGV97185.1; -; Genomic_DNA.
DR AlphaFoldDB; G3H0S5; -.
DR STRING; 10029.G3H0S5; -.
DR InParanoid; G3H0S5; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16611; RING-HC_TRIM69_C-IV; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF286; E3 UBIQUITIN-PROTEIN LIGASE TRIM69; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 5..46
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 230..424
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 128..224
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 424 AA; 49092 MW; 5CF65555FFFD1B0C CRC64;
MELHCPLCND WFRDPLMLSC GHNFCQACIQ NYWKLHAKET FCPECKMLCQ YSNCTFNLVL
EKLVEKIKKL PLLKGHPQCP EHGENLKLFS KPDGKLICFQ CKDARLSMGQ SKDFLQISDA
VRFFTEELSL YQNQLQTVLK ELQSLRNMQK DAIAAYKDNK IQMQQYLSLE FLKLHQFLHN
KEKDILNELR DEGKVLNEEM ELNLNQLQEQ CLLAKDMLMN IQARMEQNSF NFLKVRFHTD
LIMGTRLSQL TLDPKTAHPN LVLSKSRTSV CHGDVKQVMP DDPERFDSSV AVLGSKGFTS
GKWYWEVEVA KKTKWTVGVV RESIIRKGSC PLTPEQGFWL LRLRNQTDLK ALDLPSCSLK
LDDLNRVGIY LDYEGGQLSF YNASTMTHLY TFGSHFTEKL FPYFCPCLND GGENKEPLHI
VHPQ
//
