ID G3H339_CRIGR Unreviewed; 704 AA.
AC G3H339;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Leucine-rich repeat neuronal protein 1 {ECO:0000313|EMBL:EGV92029.1};
GN ORFNames=I79_004648 {ECO:0000313|EMBL:EGV92029.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV92029.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000122; EGV92029.1; -; Genomic_DNA.
DR AlphaFoldDB; G3H339; -.
DR STRING; 10029.G3H339; -.
DR PaxDb; 10029-XP_007608176-1; -.
DR eggNOG; KOG0619; Eukaryota.
DR InParanoid; G3H339; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373:SF97; LEUCINE-RICH REPEAT NEURONAL PROTEIN 1; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13855; LRR_8; 3.
DR Pfam; PF01463; LRRCT; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00365; LRR_SD22; 4.
DR SMART; SM00369; LRR_TYP; 9.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 619..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 412..505
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 513..605
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 679..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 79407 MW; 931994DFA71C6995 CRC64;
MVLSLLMTSL TESSILNSEC PQLCVCEIRP WFTPQSTYRE ATTVDCNDLR LTRIPSNLSS
DTQVLLLQSN NIAKTVGELQ QLFNLTELDF SQNNFTNIKE VGLANLTQLT TLHLEENQIS
EMTDYCLQDL SNLQELYINH NQISTISANA FSGLKNLLRL HLNSNKLKVI DSRWFDSTPN
LEILMIGENP VIGILDMNFR PLSNLRSLVL AGMYLTDVPG NALVGLDSLE SLSFYDNKLI
KVPQLALQKV PNLKFLDLNK NPIHKIQEGD FKNMLRLKEL GINNMGELVS VDRYALDNLP
ELTKLEATNN PKLSYIHRLA FRSVPALESL MLNNNALNAV YQKTVESLPN LREISIHSNP
LRCDCVIHWI NSNKTNIRFM EPLSMFCAMP PEYRGQQVKE VLIQDSSEQC LPMISHDTFP
NHLNMDIGTT VFLDCRAMAE PEPEIYWVTP IGNKITVETL SDKYKLSNEG TLEIANIQIE
DSGRYTCVAQ NVQGADTRVA AIKVNGTLLD GAQVLKIYVK QTESHSILVS WKVNSNVMTS
NLKWSSATMK IDNPHITYTA RVPVDVHEYN LTHLQPSTDY EVCLTVSNIH QQTQKSCVNV
TTKNAAFTLD ISDHETSTAL AAVMGSMFAV ISLASIAVYI AKRFKRKNYH HSLKKYMQKT
SSIPLNELYP PLINLWEGDS EKDKDGSADT KPTQVDTSRS YYMW
//
