ID G3H6P5_CRIGR Unreviewed; 479 AA.
AC G3H6P5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Tripartite motif-containing protein 60 {ECO:0000313|EMBL:EGV92633.1, ECO:0000313|RefSeq:XP_027249852.1};
GN Name=LOC100756234 {ECO:0000313|RefSeq:XP_027249852.1};
GN ORFNames=I79_006012 {ECO:0000313|EMBL:EGV92633.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV92633.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGV92633.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_027249852.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_027249852.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_027249852.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; JH000179; EGV92633.1; -; Genomic_DNA.
DR RefSeq; XP_003499916.2; XM_003499868.3.
DR RefSeq; XP_007628010.1; XM_007629820.2.
DR RefSeq; XP_027249852.1; XM_027394051.2.
DR PaxDb; 10029-XP_007628010-1; -.
DR GeneID; 100756234; -.
DR KEGG; cge:100756234; -.
DR eggNOG; KOG2177; Eukaryota.
DR InParanoid; G3H6P5; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP001108280; Chromosome 1.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15828; SPRY_PRY_TRIM60; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR035786; SPRY/PRY_TRIM60.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF677; TRIPARTITE MOTIF-CONTAINING PROTEIN 61-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 26..67
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 280..478
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 98..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 55173 MW; 84342DC64D815D54 CRC64;
MSSPTKLQGS MELKAAQVDL QAEAHCPICK EDFKNRVTIG CRHDFCHACI SEFWKDRKGS
FPCPVCHFNC PEGKFWSHEH LSQATEVSQP LPVKKIRNSP QGTCSSEMRP QPPAPCSGKD
QEVFSPSPTS HFVWPIEDAA LCTREQIEFY IKMWREKVEP AEKAIATQRR RSLELKRRVH
LRREEVMSEY QQYMLILQNE EKSILEQLEN EKVIALAKMN KNLENFSEHM SSLKCLLMEV
EKKCAKSELE LLASVKDVYK RNKNLECPRI VFFELKVRSL VLPPQYSGLD RIIKQFHVDV
TLDPETAHCR LDVSEDKKAV LYGQMKELPN NQRRFHMYPI VLGSEGYSSG RQYWEVAVEH
MCDWFLGVCK EPFPRSMDRS KNEQQPFSLQ DGLWGVGLTS CQDYIGLGLK KIDLLPKVAP
NRVGIFLDSD LHEVSFYNLS DKSLLCHFSD CASGALWPYF YTGYASVPLK ICTAEDPEW
//
