ID G3H7E4_CRIGR Unreviewed; 524 AA.
AC G3H7E4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=JRK like {ECO:0000313|Ensembl:ENSCGRP00001008618.1};
DE SubName: Full=Jerky protein homolog-like {ECO:0000313|RefSeq:XP_027270944.1};
DE SubName: Full=Jerky protein-like-like {ECO:0000313|EMBL:EGW00893.1};
GN Name=Jrkl {ECO:0000313|Ensembl:ENSCGRP00001008618.1,
GN ECO:0000313|RefSeq:XP_027270944.1};
GN ORFNames=I79_006275 {ECO:0000313|EMBL:EGW00893.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW00893.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW00893.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001008618.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:XP_027270944.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_027270944.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_027270944.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR EMBL; JH000193; EGW00893.1; -; Genomic_DNA.
DR RefSeq; XP_003500130.1; XM_003500082.3.
DR RefSeq; XP_007631633.1; XM_007633443.2.
DR RefSeq; XP_027270944.1; XM_027415143.2.
DR STRING; 10029.G3H7E4; -.
DR PaxDb; 10029-XP_007631633-1; -.
DR Ensembl; ENSCGRT00001012747.1; ENSCGRP00001008618.1; ENSCGRG00001010876.1.
DR GeneID; 100763189; -.
DR KEGG; cge:100763189; -.
DR CTD; 8690; -.
DR eggNOG; KOG3105; Eukaryota.
DR GeneTree; ENSGT00940000161513; -.
DR OMA; SRAWKQI; -.
DR OrthoDB; 2967227at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR Proteomes; UP001108280; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR19303:SF16; JERKY PROTEIN HOMOLOG-LIKE; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT DOMAIN 1..52
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 67..139
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 28..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
SQ SEQUENCE 524 AA; 59828 MW; 8516D6DC4B18009C CRC64;
MSGKRKRVVL TIKDKLDIIK KLEDGGSSKQ LAVIYGIGET TVRDIRKNKE KIITYASSSD
STSLLAKRKS MKPSMYEELD RAMLEWFNQQ RAKGNPVSGS ICAKRAEFFF YALGMDGDFN
PSAGWLTRFK QRHSIREINI RNERLSGDDR AVEDFCKNFR DFIERENLQP EQIYNADETG
LFWKCLPSRT SVIKGKRTVP GHNSFEERVT VMCCTNATGL HKLKLCVVGK AKKPRSFKST
DTLNLPVSYF SQKGAWMDLS IFRQWFDKIF VPQVREYLRS KGLQEKAVLL LDNSPAHPNE
NVLRSDDGQI FAKCLPPNIA SSIQPLDQGV IATMKRNYRA GLLQNNLEEG NDLKSFWKKL
TLLDALYEIA MAWNLVKPVT ISRAWKQILP SIEEKEGLDF DEEDISGATV ATILQHTKGL
ENVTPENMEK WLEIDSTEPG YEVLTDSEII RRAQGQTDES SENDEEGIEL IPEKHINHAA
ALQWTENLLD YLEQQGDMIL PDRLVVRKLR ATIRNKQKMT NPSQ
//
