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Database: UniProt
Entry: G3H7X9_CRIGR
LinkDB: G3H7X9_CRIGR
Original site: G3H7X9_CRIGR 
ID   G3H7X9_CRIGR            Unreviewed;       615 AA.
AC   G3H7X9;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   23-MAY-2018, entry version 16.
DE   SubName: Full=Nicastrin {ECO:0000313|EMBL:EGV93395.1};
GN   ORFNames=I79_006475 {ECO:0000313|EMBL:EGV93395.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV93395.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W.,
RA   Xie M., Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B.,
RA   Koh W., Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J.,
RA   Quake S.R., Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell
RT   line.";
RL   Nat. Biotechnol. 29:735-741(2011).
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DR   EMBL; JH000204; EGV93395.1; -; Genomic_DNA.
DR   PRIDE; G3H7X9; -.
DR   InParanoid; G3H7X9; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016485; P:protein processing; IEA:InterPro.
DR   InterPro; IPR008710; Nicastrin.
DR   PANTHER; PTHR21092; PTHR21092; 1.
DR   Pfam; PF05450; Nicastrin; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001075};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    576    596       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   615 AA;  68661 MW;  D94886BBF3F5DA49 CRC64;
     MVLLEGKLFN RAVMEKLKGR TSRIAGLAVT LAKPNSTSSF SPSVQCPNDG FGIYSNSYGS
     EFAHCKQTLW NELGNGLAYE DFSFPIFLLE DENETKVIKQ CYQDHNLAQN GSAPRFPLCA
     MQLFSHMHAV ISTATCMRRS FIQSTFSINP EIVCDPLSDY NVWSMLKPIN TSGALEPDDR
     VVVAATRLDS RSFFWNVAPG AESAVASYVT QLAAAEALHK ASDVATLPRN VMFVFFQGET
     FDYIGSSRMV YDMENGKFPV RLENIDSFVE LGQVALRTSL DLWMHTDPMS QKNESVKNQV
     EDLLVTLEKS GAGVPEVVLR RQNQSQALPP SSLQRFLRAR NISGVVLADH SGSFHNRYYQ
     SIYDTAENIN VTYPERQSPE EDLNFVTDTA KALANVATVL ARALYELAGG TNFSDSIQAD
     PQTVTRLLYG FLVRANNSWF QSILRQDLRS YLDDGPLQHY IAVTSPTNTT YVVQYALANL
     TGKVTNLTRE QCQDPSKVPN ESKALYDYSW VQGPLNSNKT ERLPRCVRST VRLARALSPA
     FELSQWGSTE YSTWAESRWK DIQARIFLVA SKELEFITLT VGFGILIFSL IVTYCINAKA
     DVLFVAPREP GAVSY
//
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