ID G3HBN4_CRIGR Unreviewed; 1073 AA.
AC G3HBN4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=C-jun-amino-terminal kinase-interacting protein 3 {ECO:0000313|EMBL:EGW04423.1};
GN ORFNames=I79_007938 {ECO:0000313|EMBL:EGW04423.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW04423.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000273; EGW04423.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HBN4; -.
DR STRING; 10029.G3HBN4; -.
DR PaxDb; 10029-XP_007606654-1; -.
DR eggNOG; KOG2077; Eukaryota.
DR InParanoid; G3HBN4; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0005078; F:MAP-kinase scaffold activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.1000; arf6 gtpase in complex with a specific effector, jip4; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR039911; JIP3/JIP4.
DR InterPro; IPR032486; JIP_LZII.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR13886:SF3; C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 3; 1.
DR PANTHER; PTHR13886; JNK/SAPK-ASSOCIATED PROTEIN; 1.
DR Pfam; PF16471; JIP_LZII; 1.
DR Pfam; PF19056; WD40_2; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS51777; RH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Kinase {ECO:0000313|EMBL:EGW04423.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transferase {ECO:0000313|EMBL:EGW04423.1}.
FT DOMAIN 257..331
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1033..1053
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 185..233
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..502
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1073 AA; 116938 MW; B8B5B1021FC42B94 CRC64;
MSESGQSSAA ATPSTTGTKS NTPTSSVPSA AVTPLNESLQ PLGDYGSVTK NNKRAREKRN
SRNMEVQVTQ EMRNVSIGMG SSDEWSDVQD IIDSTPELDV CPETRLDRTG SSPTQGIVNK
AFGINTDSLY HELSTAGSEV IGDVDEGADL LGMGKEVGNL LLENSQLLET KNALNVVKND
LIAKVDQLSG EQEVLKGELE AAKQAKVKLE NRIKELEEEL KRVKSEAVIA RREPREEVED
VSSYLCTELD KIPMAQRRRF TRVEMARVLM ERNQYKERLM ELQEAVRWTE MIRASREHPS
VQEKKKSTIW QFFSRLFSSS SSPPPAKRSY PSVNIHYKSP TTAGFSQRRS HAMCQISAGS
RPLEFFPDDD CTSSARREQK REQYRQVREH VRNDDGRLQA CGWSLPAKYK QLSPNGGQED
NRMKNVPVPV YCRPLVEKDP TMKLWCAAGV NLSGWKPNEE DSSNGAKPTP GRDPLTCDRE
VEGEPKSSHP SPEKKKAKEV SEADATSSRV WILTSTLTTS KVVIIDANQP GTVVDQFTVC
NAHVLCISSI PAASDSDYPP GEMFLDSDVN PEDSGADGVL AGITLVGCAT RCNVPRSNCS
SRGDTPVLDK GQGDVAATAN GKVNPSQSTE EATEATEVPD PGPSEPEATT VRPGPLTEHV
FTDLAPTPPS STQPASENGP EPDGSIVQPQ LEPSGEPSAT TSSAAPTMWL GAQNGWLYVH
SAVANWKKCL HSIKLKDSVL SLVHVKGRVL VALADGTLAI FHRGEDGQWD LSNYHLMDLG
HPHHSIRCMA VVDDRVWCGY KNKVHVIQPK TMQIEKSFDA HPRRESQVRQ LAWIGDGVWV
SIRLDSTLRL YHAHTHQHLQ DVDIEPYVSK MLGTGKLGFS FVRITALLIA GNRLWVGTGN
GVVISIPLTE TVVLHRGQLL GLRANKTSPT SGEGTRPGGI IHVYGDDSSD KAASSFIPYC
SMAQAQLCFH GHRDAVKFFV SVPGNVLATL NGSVLDSPSE GPGPAAPAAD SEGQKLKNAL
VLSGGEGYID FRIGDGEDDE TEEGAGDVNQ VKPTLSKAER SHIIVWQVSY TPE
//
