ID G3HCU4_CRIGR Unreviewed; 211 AA.
AC G3HCU4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=B-cell antigen receptor complex-associated protein beta chain {ECO:0000313|EMBL:EGV99168.1, ECO:0000313|RefSeq:XP_035304147.1};
GN Name=Cd79b {ECO:0000313|RefSeq:XP_035304147.1};
GN ORFNames=I79_008311 {ECO:0000313|EMBL:EGV99168.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV99168.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGV99168.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_035304147.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_035304147.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_035304147.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; JH000285; EGV99168.1; -; Genomic_DNA.
DR RefSeq; XP_016826645.1; XM_016971156.1.
DR RefSeq; XP_016830812.1; XM_016975323.1.
DR RefSeq; XP_035304147.1; XM_035448256.1.
DR STRING; 10029.G3HCU4; -.
DR PaxDb; 10029-XP_007628933-1; -.
DR eggNOG; ENOG502S7X8; Eukaryota.
DR InParanoid; G3HCU4; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP001108280; Chromosome 7.
DR GO; GO:0019815; C:B cell receptor complex; IEA:InterPro.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR039695; CD79a/CD79b.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003110; Phos_immunorcpt_sig_ITAM.
DR PANTHER; PTHR14334; B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR14334:SF2; B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN BETA CHAIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF02189; ITAM; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00077; ITAM; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51055; ITAM_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|EMBL:EGV99168.1, ECO:0000313|RefSeq:XP_035304147.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..211
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041197599"
FT TRANSMEM 142..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..113
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 211 AA; 24007 MW; 34B69C72F3F60966 CRC64;
MATMVPSSVP CHWLLFLLLL FSGSSCSKIL QFPRYVAKKR NSVVKLYCSS EYSGIMTWFR
KQGNQELQEL SEEEGHISKT WNGSLHTLTI RSIQYEDNGI YFCKQQCNSA NLEIAWGCGS
ELKVLGFSTL EQLKRRNTLK DGIIMIQTLL IIVFIIVPIF LLLDKDDSKA GMEEDHTYEG
LNIDQTATYE DIVTLRTGEV KWSVGEHPGQ E
//
