ID G3HDW3_CRIGR Unreviewed; 1024 AA.
AC G3HDW3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Uncharacterized protein KIAA0319 {ECO:0000313|EMBL:EGV94310.1};
GN ORFNames=I79_008730 {ECO:0000313|EMBL:EGV94310.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV94310.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000302; EGV94310.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HDW3; -.
DR STRING; 10029.G3HDW3; -.
DR PaxDb; 10029-XP_007634613-1; -.
DR eggNOG; ENOG502QR8M; Eukaryota.
DR InParanoid; G3HDW3; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 3.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR027903; DUF4566.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR029865; KIAA0319-like.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR46182:SF1; DYSLEXIA-ASSOCIATED PROTEIN KIAA0319; 1.
DR PANTHER; PTHR46182; FI19480P1; 1.
DR Pfam; PF15130; DUF4566; 2.
DR SMART; SM00089; PKD; 4.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR SUPFAM; SSF49299; PKD domain; 3.
DR PROSITE; PS50093; PKD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 908..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 497..576
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
SQ SEQUENCE 1024 AA; 114444 MW; 6E11751ADF21AA5D CRC64;
MGDPNSRKKQ ALNRLRAQLR KKKESLADQF DFKMYIAFVF KEKKKKSALF EVSEVIPVMT
NNYEENILKG VRDSSYSLES SIELLQKDVV QLHAPRYQSM RRAKFEFHHG DYEKQFLHVL
SRKDKTGIVV NNPNQSVFLF IDRQHLQFEE SKVYQVPEAD NLWLYSPDVV FLQEVIPSYC
AYLKKRASSY KIITGNEEGY FTAILLKKGK AKFKSQEIVP FPNTKMMRNL LCVNASVGGN
EFCLMTSHLE STREHSAERI SQLKMVFQKM QEAPDSTTVI FAGDTNLRDH EPGVQPSHGG
EKLHSYSHST KHRTQHLNIC HQYSSPWADP TCVACVTYYF FKDRVILESI SILVSDLFPD
STYSYEWSLM SHPVDFQGKI TQENKPILHL SQLSVGLYTF RVTVSSENAF GEGYVNVTVM
PAARVNQPPV AVVSPQIQEL TVPLTSALID GSRVLTITDS DGATNSTMAT LIIHGAVDYP
PVANAGPNQT ITLPQNTITL NGNQSSDDHQ IVLYEWSPGP GGESKEMVMQ ATQTPYLHLS
EMQEGEYMFQ LMVTDSSGQQ STAMVAVIVQ AENNQAPVAV AGPDKELFFP VQSATLDGSR
SSDDHGIVCY HWEPIRGPSA VEMENVDKAI ATVTGLQVGT YHFRLTVRDQ QGLSSTSTLT
VAVKKKDNSP PRAQAGGRHV LTLPNNSITL DGSQSTDDGG IVSYLWIRDG QSPAAGDVIG
GSDNGVALQL TNLVEGVYTF HLLVTDSQGA SDSDTAIVEV LPDPKKDGLV ELILQVGVEQ
LTEQQKETLV RQLAILLNVL DSDVKVLKVQ AHTDVSTVII FYVQSGPPFK VLRAADVARN
LHRRLSKEKA AFLLFKVLRI DTAGCLLKCS GHGHCDPITK RCICSQLWME NLIQSYMWDG
ESNCEWSVFY VAALALTLTV LTGAVTWLCI CCCRRRKRTK IRKKTKYTIL DNMDEQERME
LRPKYGIKHR STEHNSSLMV SESEFESDQD TLFSRERMER GILKGSLNGS ARNGDSFSYC
AKDR
//
