ID G3HEJ5_CRIGR Unreviewed; 496 AA.
AC G3HEJ5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=ADP-dependent glucokinase {ECO:0000313|EMBL:EGW02121.1, ECO:0000313|Ensembl:ENSCGRP00001007393.1};
GN Name=Adpgk {ECO:0000313|Ensembl:ENSCGRP00001007393.1};
GN ORFNames=I79_008979 {ECO:0000313|EMBL:EGW02121.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW02121.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW02121.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001007393.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; JH000315; EGW02121.1; -; Genomic_DNA.
DR RefSeq; XP_003502445.1; XM_003502397.3.
DR SMR; G3HEJ5; -.
DR STRING; 10029.G3HEJ5; -.
DR PaxDb; 10029-XP_007613347-1; -.
DR Ensembl; ENSCGRT00001011426.1; ENSCGRP00001007393.1; ENSCGRG00001009816.1.
DR GeneID; 100754978; -.
DR CTD; 83440; -.
DR eggNOG; KOG4184; Eukaryota.
DR GeneTree; ENSGT00390000017953; -.
DR OMA; MWRKASA; -.
DR OrthoDB; 51859at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl.
DR GO; GO:0043843; F:ADP-specific glucokinase activity; IEA:Ensembl.
DR GO; GO:0006006; P:glucose metabolic process; IEA:Ensembl.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01938; ADPGK_ADPPFK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR007666; ADP_PFK/GK.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR21208; ADP-DEPENDENT GLUCOKINASE; 1.
DR PANTHER; PTHR21208:SF0; ADP-DEPENDENT GLUCOKINASE; 1.
DR Pfam; PF04587; ADP_PFK_GK; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS51255; ADPK; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EGW02121.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..496
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040716346"
SQ SEQUENCE 496 AA; 53872 MW; 424896A928C1D3BE CRC64;
MALWRGSACA GFLALAVGCV FLLEPELPGS ALHSLWSSLR LGPAPVSPGP LSPEGRLAAA
WDALIVQPAR RWRRVAVGVN ACVDVVISGM KLLQALGLSP GNGRDHAVLH SKSDLEEAFV
YFMGKGAAAE RFFSDKETFH DIAQTASEFP GAQHYVGGNA ALIGQRFAAN TDLKVLLCGP
IGPKLHELLD DNVFVPPESL QEVDEFHLIL EYLAGEEWGP FKAPHANRFI FSHDLSNGAM
NMLEVFVSSL EEFQPDLVVL SGLHMMEGQS KELQRKRLLE VVTSISDIPT GIPIHLELAS
MTNRELMSSI VHQQVFPAVT SLGLNEQELL FLSQSASGPH ASLSSWDGIP DVGMVSDILF
WILKEHGRSK SRSSDLTRIH FHTLVYHILA TVDGHWANQL AAVAAGARVA GTQACATETI
DASRVSLRAP QEFMTSHSES GSKIVLNPNK PVVEWHREGI TFYFTPVLVC KDPIRTVGLG
DAISAEGLFY SEAHPD
//
