ID G3HGN2_CRIGR Unreviewed; 188 AA.
AC G3HGN2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Mesogenin-1 {ECO:0000256|ARBA:ARBA00039844};
GN Name=Msgn1 {ECO:0000313|Ensembl:ENSCGRP00001002915.1,
GN ECO:0000313|RefSeq:XP_027280201.1};
GN ORFNames=I79_009770 {ECO:0000313|EMBL:EGW02734.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW02734.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
RN [2] {ECO:0000313|EMBL:EGW02734.1}
RP NUCLEOTIDE SEQUENCE.
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan C.H., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary CHO-K1 cell line.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSCGRP00001002915.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:XP_027280201.1}
RP IDENTIFICATION.
RC STRAIN=17A/GY {ECO:0000313|RefSeq:XP_027280201.1};
RC TISSUE=Liver {ECO:0000313|RefSeq:XP_027280201.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; JH000357; EGW02734.1; -; Genomic_DNA.
DR RefSeq; XP_003503093.1; XM_003503045.1.
DR RefSeq; XP_007620983.1; XM_007622793.1.
DR RefSeq; XP_027280201.1; XM_027424400.1.
DR STRING; 10029.G3HGN2; -.
DR PaxDb; 10029-XP_007620983-1; -.
DR Ensembl; ENSCGRT00001004047.1; ENSCGRP00001002915.1; ENSCGRG00001003369.1.
DR GeneID; 100755379; -.
DR KEGG; cge:100755379; -.
DR CTD; 343930; -.
DR eggNOG; KOG4029; Eukaryota.
DR GeneTree; ENSGT00530000063712; -.
DR OMA; SSWDWKN; -.
DR OrthoDB; 5354298at2759; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR Proteomes; UP000694386; Unplaced.
DR Proteomes; UP001108280; Chromosome 7.
DR GO; GO:0003682; F:chromatin binding; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IEA:Ensembl.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007379; P:segment specification; IEA:Ensembl.
DR GO; GO:0001756; P:somitogenesis; IEA:Ensembl.
DR CDD; cd18939; bHLH_TS_Msgn1; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR040259; Mesogenin/MesP.
DR PANTHER; PTHR20937; IP14615P; 1.
DR PANTHER; PTHR20937:SF4; MESOGENIN-1; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Reference proteome {ECO:0000313|Proteomes:UP000001075}.
FT DOMAIN 118..172
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
SQ SEQUENCE 188 AA; 20371 MW; 00EEC867C1A07C29 CRC64;
MDNLGETFLN LEDGLDASDT VGLLASWDWK SRARPLELSQ ASPTQSLSPV PSLESYSEVA
LPCGHSGASI GGSDGFSSHG AGGLVELDYS MLAFQPAYLQ ASGGLKGQKG SKVKMSVQRR
RKASEREKLR MRTLADALHT LRNYLPPVYS QRGQPLTKIQ TLKYTIKYIG ELTDLLNGGG
RESRPQSV
//
