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Database: UniProt
Entry: G3HJA6_CRIGR
LinkDB: G3HJA6_CRIGR
Original site: G3HJA6_CRIGR 
ID   G3HJA6_CRIGR            Unreviewed;      1261 AA.
AC   G3HJA6;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   23-MAY-2018, entry version 30.
DE   SubName: Full=Ryanodine receptor 1 {ECO:0000313|EMBL:EGV93016.1};
GN   ORFNames=I79_010748 {ECO:0000313|EMBL:EGV93016.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGV93016.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W.,
RA   Xie M., Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B.,
RA   Koh W., Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J.,
RA   Quake S.R., Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell
RT   line.";
RL   Nat. Biotechnol. 29:735-741(2011).
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DR   EMBL; JH000426; EGV93016.1; -; Genomic_DNA.
DR   PRIDE; G3HJA6; -.
DR   InParanoid; G3HJA6; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR033215; RyR1.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 6.
DR   PANTHER; PTHR13715:SF15; PTHR13715:SF15; 6.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 2.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50919; MIR; 4.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001075};
KW   Receptor {ECO:0000313|EMBL:EGV93016.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       85    140       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      147    192       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      198    252       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      258    315       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      675    867       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED     1122   1179       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1261 AA;  140670 MW;  7296CD0D38E2BC5D CRC64;
     MTKWSCSAAX XXXXXXXXXX XXXXXXXXXP TRLCFLEPTS NAQNVPPDLA ICCFILEQSL
     SVRALQEMLA NTVEAGVESS QGGGHRTLLY GHAILLRHAH SRMYLSCLTT SRSITDKLAF
     DVGLQEDATG EACWWTMHPA SKQRSEGEKV RVGDDLILVS VSSERYLHLS TASGELQVDA
     SFMQTLWNMN PICSGCEEGF VTGGHVLRLF HGHMDECVTI SPSDSDDQRR LVYYEGGPVC
     THARSLWRLE PLRISWSGSH LRWGQPLRIR HVTTGRYLAL TEDQGLVVVD ASKAHTKATS
     FCFRISKEKL DVAPKRDVEG MGPPEIKYGE SLCFVQHVAS GLWLTYAAPD PKALRLGVLK
     KKGMLSLVLN CIDRLNVYTT AAHFAEFAGE EAAESWKEIV NLLYELLASL IRGNRTNCAL
     FSTNLDWLVS KLDRLEASSG ILEVLYCVLI ESPEVLNIIQ ENHIKSIISL LDKHGRNHKD
     VGHVARPVTS PGQHLLAPED VVSCCLDLSV PSISFRINGC PVQGVFESFN LDGLFFPVVS
     FSAGINPCLS DLDFVPCPVD TIQIVLPPHL ERIREKLAEN IHELWALTRI EQGWTYGPVS
     LDSEGEGQGW TLLALGCHVG MADEKAEDNL KKTKLPKTYM MSNGYKPAPL DLSHVRLTPA
     QTTLVDRLAE NGHNVWARDR VAQGWSYSAV QDIPARRNPR LVPYRLLDEA TKRSNRDSLC
     QAVRTLLGYG YNIEPPDQEP IQSGRWYFEF EAVTTGEMRV GWARPELRPD VELGADDLAY
     VFNGHRGQRW HLGSEPFGRP WQPGDVVGCM IDLTENTIIF TLNGEVLMSD SGSETAFRDI
     EIGDGFLPVC SLGPGQVGHL NLGQDVSSLC FFAICGLQEG FEPFAINMQR PVTTWFSKSL
     PQFEPVPLEH PHYEVARMDG TVDTPPCLRL THRTWGSQNS LVEMLFLRLS LPVQFHQHFR
     CTAGATPLAS PGLQPPAEDE ARAAEPDTDY ENLRRSAGGW GEVEGGKEGT AKEGAPGGTA
     QAGAEAQPTR VENEKDDTTE KNKKRGQVDL CEFLFKAKKV AMMTQPPATP SLPRLPRDVV
     PADNRDDPEI ILNTTTNFMP LSAAMFQTTD VKQILKMIEP EVFTEEEEEE EKEEEEEEDE
     EEKEEDEEEE EAHEKEDEEK EEEEEEEAAE EEAAELEEGL LQLTLPESVK LQMCHLLEYF
     CDQELQHRVE SLAAFAECYV DKLQANQRGR YGLLMTASSM SAAETARRTR EFRSPPQEQV
     L
//
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