ID G3HN11_CRIGR Unreviewed; 635 AA.
AC G3HN11;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Iporin {ECO:0000313|EMBL:EGW07889.1};
GN ORFNames=I79_012141 {ECO:0000313|EMBL:EGW07889.1};
OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea;
OC Cricetidae; Cricetinae; Cricetulus.
OX NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW07889.1, ECO:0000313|Proteomes:UP000001075};
RN [1] {ECO:0000313|Proteomes:UP000001075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX PubMed=21804562; DOI=10.1038/nbt.1932;
RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., Xie M.,
RA Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., Koh W.,
RA Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., Quake S.R.,
RA Famili I., Palsson B.O., Wang J.;
RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line.";
RL Nat. Biotechnol. 29:735-741(2011).
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DR EMBL; JH000529; EGW07889.1; -; Genomic_DNA.
DR AlphaFoldDB; G3HN11; -.
DR STRING; 10029.G3HN11; -.
DR PaxDb; 10029-XP_007625371-1; -.
DR eggNOG; ENOG502QR1I; Eukaryota.
DR InParanoid; G3HN11; -.
DR Proteomes; UP000001075; Unassembled WGS sequence.
DR CDD; cd17702; RUN_RUSC2; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047342; RUN_RUSC2.
DR InterPro; IPR047343; RUSC1_2.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15591:SF14; AP-4 COMPLEX ACCESSORY SUBUNIT RUSC2; 1.
DR PANTHER; PTHR15591; RUN AND SH3 DOMAIN CONTAINING; 1.
DR Pfam; PF02759; RUN; 1.
DR Pfam; PF07653; SH3_2; 1.
DR SMART; SM00593; RUN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 153..297
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 566..625
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 332..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..488
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 69446 MW; 84B175764191A407 CRC64;
MASRPNNANH LSPQALKWRE YRMKNPLLAP GLSGSLDRRP QEARLARRNP IFEFPGSLGA
ANHLNYRLNG QVAKPLPLTC PDLQDPFSLA EKPPAEFCLS PDGTSEAISI DVLQKKGLVK
AVNTAVDLIV AHFGTSRDPG VKAKLGNSSV SPNVGHLVLK YLCPAVQAVL EDGLKAFVLD
VIIGQRKNMP WSVVEASTQL GPSTKVLHGL YNKVSQFPEL TSHTMRFNAF ILGLLNIRSL
EFWFNHLYNH EDIIQTHYQP WGFLRAAHTV CPGLFEELLL LLQPLALLPF NLDLLFQHRL
LQSGQQQRQH KELLRVSQDL LLSAHSTLQL ARARGQEGPG DADRVATGER VKGVGASEGG
EEDEEDREEA DEVVGSSEHS RWTRGGQAGW WYQLMQSSQV YIDGTAEGSR FPRSSSSGSE
KKKGVGSGGP SQAPPPREGV VEGAEACPAP EEALSQERGW PFWMGSPPDS VLAELRRSRE
REGPVAPPTE NEERTAEPAP GGIKWGHLFG SRKAQREARP TNRLPSDWLS LDKSVFQLVA
QTMGARREPE PRENLQESHS PALSSKPPCE VQALCHHLAT GPGQLSFHKG DILRVLGPAG
GDWLRCSRGP DTGLVPLAYV TLTPTPSSPP GSSQN
//
