GenomeNet

Database: UniProt
Entry: G3HS42_CRIGR
LinkDB: G3HS42_CRIGR
Original site: G3HS42_CRIGR 
ID   G3HS42_CRIGR            Unreviewed;       809 AA.
AC   G3HS42;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   23-MAY-2018, entry version 20.
DE   SubName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 {ECO:0000313|EMBL:EGW06975.1};
GN   ORFNames=I79_013668 {ECO:0000313|EMBL:EGW06975.1};
OS   Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
OC   Muroidea; Cricetidae; Cricetinae; Cricetulus.
OX   NCBI_TaxID=10029 {ECO:0000313|EMBL:EGW06975.1, ECO:0000313|Proteomes:UP000001075};
RN   [1] {ECO:0000313|Proteomes:UP000001075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHO K1 cell line {ECO:0000313|Proteomes:UP000001075};
RX   PubMed=21804562; DOI=10.1038/nbt.1932;
RA   Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W.,
RA   Xie M., Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B.,
RA   Koh W., Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J.,
RA   Quake S.R., Famili I., Palsson B.O., Wang J.;
RT   "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell
RT   line.";
RL   Nat. Biotechnol. 29:735-741(2011).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; JH000650; EGW06975.1; -; Genomic_DNA.
DR   PRIDE; G3HS42; -.
DR   InParanoid; G3HS42; -.
DR   Proteomes; UP000001075; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR021930; Heparan_SO4_deacetylase.
DR   InterPro; IPR037359; NST/OST.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR10605; PTHR10605; 3.
DR   Pfam; PF12062; HSNSD; 2.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001075};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001075};
KW   Transferase {ECO:0000313|EMBL:EGW06975.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     18     39       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       43    298       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      300    457       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      538    785       Sulfotransfer_1. {ECO:0000259|Pfam:
FT                                PF00685}.
SQ   SEQUENCE   809 AA;  92952 MW;  CF825757F9043EA6 CRC64;
     MPALACLRRL CRHMSPQAVL FLLFVFCLFS VFVSAYYLYG WNRDPLVLVF VESLYSQLGQ
     EVVAILESSR FKYRTEIAPG KGDMPTLTDK GRGRFALIIY ENILKYVNLD AWNRELLDKY
     CVAYGVGIIG FFKANENSLL SAQLKGFPLF LHSNLGLKDC SINPKSPLLY VTRPSEVEKG
     VLPGEDWTVF QSNHSTYEPV LLAKTRSSES IPHLGADAGL HAALHATVVQ DLGLHDGIQR
     VLFGNNLNFW LHKLVFVDAV AFLTGKRLSL PLDRYILVDI DDIFVGKEGT RMKVEDVKDE
     GTDAEDAGDD LLLSYVKEFW WFPHMWSHMQ PHLFHNQSVL AEQMALNKKF AVEHGIPTDM
     GYAVAPHHSG VYPVHVQLYE AWKQVWSIRV TSTEEYPHLK PARYRRGFIH NGIMASGWRG
     MVLPRQTCGL FTHTIFYNEY PGGSSELDKI INGGELFLTV LLNPISIFMT HLSNYGNDRL
     GLYTFKHLVR FLHSWTNLRL QTLPPVQLAQ KYFQIFSEEK DPLWQDPCED KRHKDIWSKE
     KTCTTALYLF LGMHPDLSSN YPSSETFEEI QFFNGHNYHK GIDWYMEFFP IPSNTTSDFY
     FEKSANYFDS EVAPRRAATL LPKAKILTIL INPADRAYSW YQHQRAHDDP VALKYTFHEV
     ITAGPDASSK LRALQNRCLV PGWYATHIER WLSAFHANQI LVLDGKLLRT EPAKVMDTVQ
     KFLGVTSTVD YHKTLAFDPK KGFWCQLLEG GKTKCLGKSK GRKYPEMDLD SRAFLKDYYR
     DHNIELSKLL YKMGQTLPTW LREDLQNTR
//
DBGET integrated database retrieval system